Evidence map›Paper›PMID 34388114›Full record

ArticleAging2021

FK506 binding protein 10: a key actor of collagen crosslinking in clear cell renal cell carcinoma.

Yubai Zhang, Yue Yin, Sijia Liu, Lei Yang, Changhua Sun, Ruihua An

Open access · hybridAbstract read
In one paragraph

Article in Aging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yubai ZhangDepartment of Urology Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Yue YinDepartment of Oncology Radiotherapy, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Sijia LiuDepartment of Gynecological Radiotherapy, The Affiliated Tumor Hospital of Harbin Medical University, Harbin, China.
Lei YangDepartment of Urology Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
Changhua SunDepartment of Urology Surgery, The First Hospital of Harbin, Harbin, China.
Ruihua AnDepartment of Urology Surgery, The First Affiliated Hospital of Harbin Medical University, Harbin, China.
First Affiliated Hospital of Harbin Medical University · CNHarbin Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clear cell renal cell carcinoma (ccRCC) is the most common type of malignant tumor in the kidney. With numbers of patients whose physical condition or tumor stage not suitable for radical surgery, they only have a narrow choice of using VEGF/mTOR targeted drugs to control their tumors, but ccRCC often shows resistance to these drugs. Therefore, identifying a new therapeutic target is of urgent necessity. In this study, for the first time, we concluded from bioinformatics analyses and

Indexed as

Biomarkers, TumorCarcinoma, Renal CellCollagen Type IDatabases, GeneticGene Expression Regulation, NeoplasticHumansKaplan-Meier EstimateKidney NeoplasmsProcollagen-Lysine, 2-Oxoglutarate 5-DioxygenasePrognosisTacrolimus Binding ProteinsBiomarkers, TumorCollagen Type IFKBP10 protein, humanPLOD2 protein, humanProcollagen-Lysine, 2-Oxoglutarate 5-DioxygenaseTacrolimus Binding Proteinsclear cell renal cell carcinomacollagen synthesisFKBP10prognosis

Identifiers

PMID34388114
PMCPMC8386577
OpenAlexW3192878766

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.