Evidence map›Paper›PMID 34388045›Full record

ArticleJournal of adolescent and young adult oncology2022

Short-Term Changes in Skeletal Muscle Mass After Anthracycline Administration in Adolescent and Young Adult Sarcoma Patients.

Savannah V Wooten, Michael Roth, John Andrew Livingston, Michelle A T Hildebrandt, Joya Chandra, Behrang Amini, Eugenie S Kleinerman, Susan C Gilchrist

Open access · greenAbstract read
In one paragraph

Article in Journal of adolescent and young adult oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Diversity in chemotherapy-induced cachexia.American journal of physiology. Cell physiology · 2025
    Review
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Savannah V WootenDepartment of Pediatrics Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.ORCID 0000-0001-7811-5447
Michael RothDivision of Pediatrics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
John Andrew LivingstonDivision of Pediatrics, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Michelle A T HildebrandtDepartment of Lymphoma/Myeloma, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Joya ChandraDepartment of Pediatrics Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Behrang AminiDepartment of Musculoskeletal Imaging, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Eugenie S KleinermanDepartment of Pediatrics Research, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
Susan C GilchristDepartment of Clinical Cancer Prevention, The University of Texas M.D. Anderson Cancer Center, Houston, Texas, USA.
The University of Texas MD Anderson Cancer Center · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Fabien Delerue · 1985 to 2026
$290.8M
NCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

Identification of anthracycline-induced muscle loss is critical for maintaining health in adolescent and young adult (AYA) cancer patients. We used routine chest computed tomography (CT) scans to investigate changes in skeletal muscle of 16 AYA sarcoma patients at thoracic vertebrae 4 (T4) after anthracycline treatment. CT images were examined at three time points (prechemotherapy, postchemotherapy, and 1 year). Significant changes in total skeletal muscle index and density were seen after chemotherapy (

Indexed as

SarcomaSarcopeniaSoft Tissue NeoplasmsAdolescentAnthracyclinesHumansMuscle, SkeletalRetrospective StudiesYoung AdultAnthracyclinesanthracyclinescomputed tomographymuscle losssarcomasarcopeniaT4

Identifiers

PMID34388045
PMCPMC9529368
OpenAlexW3191412223

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.