Evidence map›Paper›PMID 34387812›Full record

ArticleNeurochemical research2021

Glutamate, Glutamine, GABA and Oxidative Products in the Pons Following Cortical Injury and Their Role in Motor Functional Recovery.

Laura E Ramos-Languren, Alberto Avila-Luna, Gabriela García-Díaz, Roberto Rodríguez-Labrada, Yaimee Vázquez-Mojena, Carmen Parra-Cid, Sergio Montes, Antonio Bueno-Nava, Rigoberto González-Piña

Abstract read
PubMed Publisher
In one paragraph

Article in Neurochemical research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 6 institutions in 2 countries.

Laura E Ramos-LangurenFaculty of Psychology, Coordination of Psychobiology and Neurosciences, National Autonomous University of Mexico, Av. Universidad 3040 Col, Copilco Universidad Alcaldía Coyoacán, 04510, Mexico City, Mexico.ORCID http://orcid.org/0000-0001-6006-8275
Alberto Avila-LunaNational Institute of Rehabilitation LGII, Calz. Mexico-Xochimilco #289 Col. Arenal de Guadalupe Alcaldía Tlalpan, 14389, Mexico City, Mexico.ORCID http://orcid.org/0000-0002-4542-1883
Gabriela García-DíazSection of Postgraduate Studies and Research, High Medical School, IPN. Salvador Diaz Miron Alcaldia Miguel Hidalgo, 11340, Mexico City, Mexico.ORCID http://orcid.org/0000-0002-1734-6732
Roberto Rodríguez-LabradaSchool of Physical Culture, University of Holguín, Avenida XX Aniversario, 80100, Holguín, Cuba.ORCID http://orcid.org/0000-0003-3193-7683
Yaimee Vázquez-MojenaCuban Centre for Neurosciences, Calle 190 entre 25 y 27, Playa, 11300, Havana City, Cuba.ORCID http://orcid.org/0000-0002-5994-4562
Carmen Parra-CidNational Institute of Rehabilitation LGII, Calz. Mexico-Xochimilco #289 Col. Arenal de Guadalupe Alcaldía Tlalpan, 14389, Mexico City, Mexico.ORCID http://orcid.org/0000-0003-1251-4271
Sergio MontesReynosa-Aztlan Multidisciplinary Unit, Autonomous University of Tamaulipas, Fuente de Diana, Aztlán, 88740, Tamaulipas, Mexico.ORCID http://orcid.org/0000-0002-0138-0784
Antonio Bueno-NavaNational Institute of Rehabilitation LGII, Calz. Mexico-Xochimilco #289 Col. Arenal de Guadalupe Alcaldía Tlalpan, 14389, Mexico City, Mexico.ORCID http://orcid.org/0000-0003-0291-4554
Rigoberto González-PiñaLaboratory of Aging Biology, National Geriatric Institute, Av. Contreras 428 Col. San Jerónimo Lídice Alcaldía Magdalena Contreras, 10200, Mexico City, Mexico. higgo@prodigy.net.mx.ORCID http://orcid.org/0000-0002-0323-043X
Tecnológico Nacional de México · MXAutonomous University of Tamaulipas · MXCuban Neuroscience Center · CUUniversidad Nacional Autónoma de México · MXUniversidad Regional Miguel Hidalgo · MXUniversity of Holguín · CU

Funding

Consejo Nacional de Ciencia y Tecnología 287614PAPIIT-UNAM IA203316
6 · The paper itself

Abstract

Brain injury leads to an excitatory phase followed by an inhibitory phase in the brain. The clinical sequelae caused by cerebral injury seem to be a response to remote functional inhibition of cerebral nuclei located far from the motor cortex but anatomically related to the injury site. It appears that such functional inhibition is mediated by an increase in lipid peroxidation (LP). To test this hypothesis, we report data from 80 rats that were allocated to the following groups: the sham group (n = 40), in which rats received an intracortical infusion of artificial cerebrospinal fluid (CSF); the injury group (n = 20), in which rats received CSF containing ferrous chloride (FeCl

Indexed as

Recovery of FunctionAnimalsBrain Injuriesgamma-Aminobutyric AcidGlutamic AcidGlutamineLipid PeroxidationMaleMotor CortexMotor DisordersOxidative StressPonsRatsRats, Wistargamma-Aminobutyric AcidGlutamic AcidGlutamineBrain injuryCerebellumLipid peroxidationPonsRats

Identifiers

PMID34387812
OpenAlexW3188642573

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.