ArticleThe journals of gerontology. Series B, Psychological sciences and social sciences2022
Risk of Dementia Differs Across Lifestyle Engagement Subgroups: A Latent Class and Time-to-Event Analysis in Community-Dwelling Older Adults.
Article in The journals of gerontology. Series B, Psychological sciences and social sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 15 citations in OpenAlex.
- Positive change in lifestyle behaviors improve cognitive health in older adults: a 10-year cohort study.Archives of public health = Archives belges de sante publique · 2026Article
- Association of joint trajectories of dietary diversity and physical activity with cognitive function in older adults: a prospective cohort study.Frontiers in public health · 2026Article
- Latent Profiles Based on Combined Risk Factors for Cognitive Decline in European Older Adults: A Retrospective Study Based on the SHARE HCAP Project.Neurology international · 2025Article
- Blue spaces and incident dementia: Differences by geospatial and historical contexts.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- How Healthy and Unhealthy Lifestyle Behaviors Affect Cognitive Function-Evidence From Older Adults in Chinese Communities: Cross-Sectional Study.JMIR public health and surveillance · 2025Article
- Intrinsic factors associated with engagement in healthy lifestyle behaviors for dementia risk reduction in midlife.Alzheimer's & dementia. Behavior & socioeconomics of aging · 2025Article
- Cognitive function differs across healthy lifestyle behavior profiles: a 10-year population-based prospective cohort study.The journal of nutrition, health & aging · 2025Article
- Gender-specific analysis of social connection patterns and risk of dementia in community-dwelling older people.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Profiles of Lifestyle Health Behaviors and Postmortem Dementia-Related Neuropathology.The journals of gerontology. Series A, Biological sciences and medical sciences · 2024Article
- Data-driven lifestyle patterns and risk of dementia in older Australian women.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Profiles of lifestyle health behaviors and cognitive decline in older adults.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Receptive and participatory arts engagement and subsequent healthy aging: Evidence from the Health and Retirement Study.Social science & medicine (1982) · 2023Article
- Effects of social participation patterns and living arrangement on mental health of Chinese older adults: A latent class analysis.Frontiers in public health · 2022Article
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Authors and funding
7 authors at 5 institutions in 1 country.
Funding
Abstract
objectivesBetter understanding of the lifestyle activities shared among older adult subgroups may inform further health behavioral interventions that can be deployed at the group or community level. We applied latent class analysis to characterize qualitatively distinct lifestyle engagement groups, examined their differential risk of incident dementia, and compared their predictive utility to traditional activity frequency and variety scores.
methodParticipants were from the Ginkgo Evaluation of Memory Study (N = 3,068, mean age = 78.5). Lifestyle activities were measured at baseline using the Lifestyle Activity Questionnaire. All-cause dementia was screened every 6 months and cases were clinically adjudicated. Median follow-up was 6 years. Time to dementia was assessed using discrete-time proportional hazards models, adjusted for demographic and health covariates.
resultsLatent classes provided slightly poorer case discrimination than the frequency scores but identified distinct qualitative subgroups. In the 4-class model, the Variety (22%) and Intellectual (18%) lifestyle groups had high engagement in intellectual activities, whereas the Variety and Social groups (32%) had high engagement in formal social activities. Compared to the Least Active group (28%), the Variety (hazard ratio [HR] = 0.67, 95% confidence interval [CI]: 0.48, 0.93) and Intellectual (HR = 0.65, 95% CI: 0.45, 0.93) groups had significantly lower risk of incident dementia, but only among those without prevalent mild cognitive impairment. DISCUSSION: Older adults highly engaged in intellectual activities, but not necessarily social activities, had the lowest risk of incident dementia. Activity frequency scores provided only slightly better case discrimination than activity variety scores and latent classes. Latent classes of older adults differed by their amount and types of activities, which may inform intervention design.
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