Evidence map›Paper›PMID 34387040›Full record

ArticleInvestigative and clinical urology2021

Optimal duration of preoperative antibiotic treatment prior to ureteroscopic lithotripsy to prevent postoperative systemic inflammatory response syndrome in patients presenting with urolithiasis-induced obstructive acute pyelonephritis.

Jeong Woo Yoo, Kwang Suk Lee, Byung Ha Chung, Se Yun Kwon, Young Jin Seo, Kyung Seop Lee, Kyo Chul Koo

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Article in Investigative and clinical urology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeong Woo YooDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-0488-3598
Kwang Suk LeeDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0002-7961-8393
Byung Ha ChungDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0001-9817-3660
Se Yun KwonDepartment of Urology, Dongguk University Gyeongju Hospital, Dongguk University College of Medicine, Gyeongju, Korea.ORCID 0000-0003-1147-8037
Young Jin SeoDepartment of Urology, Dongguk University Gyeongju Hospital, Dongguk University College of Medicine, Gyeongju, Korea.ORCID 0000-0002-9114-8363
Kyung Seop LeeDepartment of Urology, Keimyung University Gyeongju Dongsan Hospital, Keimyung University School of Medicine, Gyeongju, Korea.ORCID 0000-0002-0554-4272
Kyo Chul KooDepartment of Urology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea. gckoo@yuhs.ac.ORCID 0000-0001-7303-6256

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThere is no consensus on the optimal duration of preoperative antibiotic treatment prior to ureteroscopic lithotripsy in patients presenting with urolithiasis-induced obstructive acute pyelonephritis (APN). We aimed to identify surgeon-modifiable, preoperative risk factors associated with postoperative systemic inflammatory response syndrome (SIRS) in these patients. MATERIALS AND

methodsThis multicenter retrospective study evaluated 115 patients who presented with urolithiasis-induced obstructive APN between January 2008 and December 2019. All patients were administered intravenous third-generation cephalosporin until culture sensitivity confirmation or until ureteroscopic lithotripsy. Data were collected for age, sex, diabetes mellitus, performance status, stone features, hydronephrosis grade, preoperative renal collecting system drainage, laboratory data, operative time, and duration of preoperative antibiotic treatment. Sensitivity analysis using Youden's index and logistic regression analysis were used to assess risk factors of postoperative SIRS.

resultsPostoperative SIRS was identified in 32 (27.8%) patients. The incidence of postoperative SIRS was higher in patients who received preoperative antibiotic treatment for fewer than 14 days (38.8% vs. 12.5%; p=0.001). Backward variable selection logistic regression analysis revealed maximal stone diameter ≥15 mm, duration of preoperative antibiotic treatment <14 days, and preoperative C-reactive protein (CRP) level ≥6.0 mg/L to be associated with higher risk of postoperative SIRS.

conclusionsPatients with urolithiasis-induced obstructive APN planned for ureteroscopic lithotripsy should be administered at least 14 days of preoperative antibiotic administration and achieve a serum CRP level ≤6.0 mg/L to minimize the risk of postoperative SIRS.

Indexed as

LithotripsyPostoperative ComplicationsPyelonephritisSystemic Inflammatory Response SyndromeUreteral ObstructionUreteroscopyAnti-Bacterial AgentsAntibiotic ProphylaxisCephalosporinsDuration of TherapyFemaleHumansMaleMiddle AgedOutcome and Process Assessment, Health CarePreoperative CareAnti-Bacterial AgentsCephalosporinsAntibioticsSystemic inflammatory response syndromeUrinary tract infectionsUrolithiasis

Identifiers

PMID34387040
PMCPMC8566789

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.