Evidence map›Paper›PMID 34386972›Full record

ArticleActa anaesthesiologica Scandinavica2021

Low mortality rates among critically ill adults with COVID-19 at three non-academic intensive care units in south Sweden.

Knut Taxbro, Andreas Granath, Ola Sunnergren, Stefanie Seifert, Milena N Jakubczyk, Magnus Persson, Anneli Hammarskjöld, Catarina Alkemark, Fredrik Hammarskjöld, RJL COVID-19 Research Group

Abstract read
In one paragraph

Article in Acta anaesthesiologica Scandinavica, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Knut TaxbroDepartment of Anaesthesia and Intensive Care Medicine, Ryhov County Hospital, Jonkoping, Sweden.ORCID 0000-0001-8711-9044
Andreas GranathDepartment of Anaesthesia and Intensive Care Medicine, Ryhov County Hospital, Jonkoping, Sweden.
Ola SunnergrenDepartment of Biomedical and Clinical Sciences, Linköping University, Linköping, Sweden.
Stefanie SeifertDepartment of Anaesthesia and Intensive Care Medicine, Ryhov County Hospital, Jonkoping, Sweden.
Milena N JakubczykDepartment of Anaesthesia and Intensive Care Medicine, Eksjö Hospital, Eksjö, Sweden.
Magnus PerssonDepartment of Anaesthesia and Intensive Care Medicine, Värnamo Hospital, Värnamo, Sweden.
Anneli HammarskjöldDepartment of Anaesthesia and Intensive Care Medicine, Ryhov County Hospital, Jonkoping, Sweden.
Catarina AlkemarkDepartment of Anaesthesia and Intensive Care Medicine, Ryhov County Hospital, Jonkoping, Sweden.
Fredrik HammarskjöldDepartment of Anaesthesia and Intensive Care Medicine, Ryhov County Hospital, Jonkoping, Sweden.
RJL COVID-19 Research Group

Funding

Futurum, the Academy for Healthcare, Jönköping County Council, Jönköping, Sweden.
6 · The paper itself

Abstract

backgroundThe COVID-19 pandemic has put an exceptional strain on intensive care units worldwide. During the first year, the survival of patients with acute hypoxaemic respiratory failure appears to have improved. We aimed to describe the mortality rates, management characteristics and two pandemic waves during the first year at three non-academic rural intensive care units in Sweden.

methodsWe retrospectively analysed all cases of COVID-19 admitted to intensive care units in Region Jönköping County during 1 year. The primary endpoint was 30-day mortality.

resultsBetween 14th March 2020 and 13th March 2021, 264 patients were admitted to undergo intensive care with confirmed SARS-CoV-2 infection. The 30-day mortality rate after the initial intensive care admission was 12.9%, and this rate remained unchanged during both pandemic waves. However, we found several distinct differences between the two pandemic waves, including an increase in the use of high-flow nasal oxygen but a decrease in invasive mechanical ventilation use, biochemical markers of inflammation, continuous renal replacement therapy and length of stay in the intensive care unit.

conclusionOur study showed that critically ill patients with COVID-19 in Sweden have a low 30-day mortality rate which compares well with results published from academic centres and national cohorts throughout Scandinavia. During the second pandemic wave, the proportion of patients receiving invasive mechanical ventilation and continuous renal replacement therapy was lower than that in the first wave. This could be the result of increased knowledge and improved therapeutic options.

Indexed as

COVID-19Critical IllnessAdultHumansIntensive Care UnitsPandemicsRespiration, ArtificialRetrospective StudiesSARS-CoV-2Swedenacute respiratory distress syndromeCOVID-19intensive careventilation

Identifiers

PMID34386972
PMCPMC8441887

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.