ArticleLancet regional health. Americas2021
Seropositivity of COVID-19 among asymptomatic healthcare workers: A multi-site prospective cohort study from Northern Virginia, United States.
Article in Lancet regional health. Americas, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.
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Who cites it
9 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- The prevalence of probable mental health disorders among hospital healthcare workers during COVID-19: A systematic review and meta-analysis.Journal of affective disorders · 2023Pooled it
- Prevalence of COVID-19 and associated factors among healthcare workers in the war-torn Tigray, Ethiopia.PloS one · 2024Article
- A network meta-analysis of risk factors of infection among close contacts of COVID-19.Heliyon · 2023Article
- Mechanical Complication of Acute Myocardial Infarction Secondary to COVID-19 Disease.Heart failure clinics · 2023Review
- Key predictors of psychological distress and wellbeing in Australian frontline healthcare workers during COVID-19 (Omicron wave).Frontiers in psychology · 2023Article
- Mechanical Complication of Acute Myocardial Infarction Secondary to COVID-19 Disease.Cardiology clinics · 2022Review
- High Incidence Rate of SARS-CoV-2 Infection in Health Care Workers at a Dedicated COVID-19 Hospital: Experiences of the Pandemic from a Large Mexican Hospital.Healthcare (Basel, Switzerland) · 2022Article
- High failure rate of ChAdOx1-nCoV19 immunization against asymptomatic infection in healthcare workers during a Delta variant surge.Nature communications · 2022Article
- A Cohort Study of Seroprevalence of Antibodies Against SARS-CoV-2 Infection Among Healthcare Workers at a Tertiary Hospital in Saudi Arabia.Infection and drug resistance · 2022Article
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Authors and funding
13 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBecause of their direct patient contact, healthcare workers (HCW) face an unprecedented risk of exposure to COVID-19. The aim of this study was to examine incidence of COVID-19 disease among asymptomatic HCW and community participants in Northern Virginia during 6 months of follow-up.
methodsThis is a prospective cohort study that enrolled healthy HCW and residents who never had a symptomatic COVID-19 infection prior to enrolment from the community in Northern Virginia from April to November 2020. All participants were invited to enrol in study, and they were followed at 2-, and 6-months intervals. Participants were evaluated by commercial chemiluminescence SARS-CoV-2 serology assays as part of regional health system and public health surveillance program to monitor the spread of COVID-19 disease.
findingsOf a total of 1,819 asymptomatic HCW enrolled, 1,473 (96%) had data at two-months interval, and 1,323 (73%) participants had data at 6-months interval. At baseline, 21 (1.15%) were found to have prior COVID-19 exposure. At two-months interval, COVID-19 rate was 2.8% and at six months follow-up, the overall incidence rate increased to 4.8%, but was as high as 7.9% among those who belong to the youngest age group (20-29 years). Seroconversion rates in HCW were comparable to the seropositive rates in the Northern Virginia community. The overall incidence of COVID-19 in the community was 4.5%, but the estimate was higher among Hispanic ethnicity (incidence rate = 15.3%) potentially reflecting different socio-economic factors among the community participants and the HCW group. Using cross-sectional logistic regression and spatio-temporal mixed effects models, significant factors that influence the transmission rate among HCW include age, race/ethnicity, resident ZIP-code, and household exposure, but not direct patient contact.
interpretationIn Northern Virginia, the seropositive rate of COVID-19 disease among HCW was comparable to that in the community.
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