ArticleEClinicalMedicine2021
Endovascular therapy for superior vena cava syndrome: A systematic review and meta-analysis.
Article in EClinicalMedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Usage, anti-inflammatory effect and safety of adjunctive acupuncture for cerebral infarction: an Apriori algorithm-based data mining and meta-analysis.Frontiers in neurology · 2025Pooled it
- A thoracic SMARCA4-deficient undifferentiated tumor: A case report.Oncology letters · 2026Article
- Patient characteristics and the safety of stent placement for malignant vena cava syndrome in Japan: a nationwide analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Observational
- Covered Endovascular Reconstruction of the Anonymous Confluence (CERAC): a technical note describing a confluence-preserving endovascular technique.CVIR endovascular · 2026Article
- Contemporary management of superior vena cava syndrome.Journal of vascular surgery. Venous and lymphatic disorders · 2026Review
- Incidence and Predictors of Stent Thrombosis Following Transcatheter Sinus Venosus Defect Closure.Pediatric cardiology · 2026Article
- International Consensus on Severe Lung Cancer-The Second Edition.Translational lung cancer research · 2026Review
- Review
- Endovascular Stenting for Malignant Superior Vena Cava Syndrome Complicated by Interstitial Pneumonia: A Report of 2 Cases.The American journal of case reports · 2026Article
- A Retrospective Analysis of Endovascular Stent Insertion for Malignant Superior Vena Cava Obstruction, Focusing on Anticoagulation Practices.Current oncology (Toronto, Ont.) · 2025Article
- Superior vena cava (SVC) stent placement in children and young adults with congenitally normal cardiac and caval anatomy.Pediatric radiology · 2025Article
- Systemic Venous Recanalization: Iliocaval and Superior Vena Cava Reconstruction in Children.Seminars in interventional radiology · 2025Review
- Endovascular Treatment for Upper Body Central Venous Obstruction.Interventional radiology (Higashimatsuyama-shi (Japan) · 2025Article
- Inferior and Superior Vena Cava Reconstruction.Cardiovascular and interventional radiology · 2024Review
- A mediastinal lesion with superior vena cava obstruction: A diagnostic and therapeutic challenge.Lung India : official organ of Indian Chest Society · 2024Article
- The difficulties of recanalization in chronic superior cava vein obstruction by penetrating diagnostic catheter, PTA, and stenting: A case report.Radiology case reports · 2024Article
- Management with right atrium to jugular and brachiocephalic vein bypass for dialysis catheter-related superior vena cava syndrome.Journal of vascular surgery cases and innovative techniques · 2023Article
- Article
- Catheter-associated superior vena cava syndrome.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2023Article
- Symptom relief, prognostic factors, and outcome in patients receiving urgent radiation therapy for superior vena cava syndrome : A single-center retrospective analysis of 21 years' practice.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2022Article
Corrections and comments
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Authors and funding
8 authors at 5 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSuperior vena cava (SVC) syndrome is caused by the obstruction of the SVC and can result in significant morbidity and mortality. In contemporary practice, endovascular therapy (ET) has become the standard of care for a majority of these patients. This study is a systematic review and meta-analysis of the available literature to assess technical success, restenosis, and recurrence of SVC syndrome following endovascular intervention.
methodsFor this meta-analysis, we conducted a systematic literature review of PubMed, Cochrane Library, and Embase databases from inception to April 14, 2021 for studies on ET for SVC syndrome. Studies included full-length journal articles on the use of ET among adults with SVC syndrome. Case reports or case series with fewer than 20 patients were excluded. We evaluated the endpoints of technical success rate, restenosis rate, and recurrence rates in SVC syndrome patients after endovascular stenting. The results of this study were calculated using random-effects models.
findingsWe identified 6,012 reports, of which 39 studies met our inclusion criteria and were included for analysis. A total of 2200 patients received ET for SVC syndrome. The weighted technical success rate was 98.8% (95% CI 98.2-99.3) with low heterogeneity (I
interpretationOur systematic review revealed high technical success, low restenosis, and low recurrence rates following ET. Collectively, these results support the paradigm of ET as an effective and safe treatment for patients with SVC syndrome.
fundingNone.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.