Evidence map›Paper›PMID 34386733›Full record

ArticleiScience2021

Closely related Lak megaphages replicate in the microbiomes of diverse animals.

Marco A Crisci, Lin-Xing Chen, Audra E Devoto, Adair L Borges, Nicola Bordin, Rohan Sachdeva, Adrian Tett, Allison M Sharrar, Nicola Segata, Francesco Debenedetti and 10 more

Open access · goldAbstract read
In one paragraph

Article in iScience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 33 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. A prevalent huge phage clade in human and animal gut microbiomes.bioRxiv : the preprint server for biology · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Host interactions of novelMicrobial genomics · 2023
    Article
  15. Host interactions of novelbioRxiv : the preprint server for biology · 2023
    Article
  16. Bacteriophages of the OrderBiomolecules · 2023
    Review
  17. Article
  18. Computational Tools for the Analysis of Uncultivated Phage Genomes.Microbiology and molecular biology reviews : MMBR · 2022
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 10 institutions in 4 countries.

Marco A CrisciInstitute of Structural and Molecular Biology, Division of Biosciences, University College London, London, UK.
Lin-Xing ChenDepartment of Earth and Planetary Science, University of California Berkeley, Berkeley, CA, USA.
Audra E DevotoInnovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA.
Adair L BorgesInnovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA.
Nicola BordinInstitute of Structural and Molecular Biology, Division of Biosciences, University College London, London, UK.
Rohan SachdevaDepartment of Earth and Planetary Science, University of California Berkeley, Berkeley, CA, USA.
Adrian TettDepartment CIBIO, University of Trento, Trento, Italy.
Allison M SharrarInnovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA.
Nicola SegataDepartment CIBIO, University of Trento, Trento, Italy.
Francesco DebenedettiBristol Veterinary School, University of Bristol, Langford, Bristol, UK.
Mick BaileyBristol Veterinary School, University of Bristol, Langford, Bristol, UK.
Rachel BurtBristol Veterinary School, University of Bristol, Langford, Bristol, UK.
Rhiannon M WoodDepartment of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Lewis J RowdenZoological Society of London, London, UK.
Paula M CorsiniQuadram Institute Bioscience, Norwich Research Park, Norwich, UK.
Steven van WindenRoyal Veterinary College, London, UK.
Mark A HolmesDepartment of Veterinary Medicine, University of Cambridge, Cambridge, UK.
Shufei LeiInnovative Genomics Institute, University of California Berkeley, Berkeley, CA, USA.
Jillian F BanfieldDepartment of Earth and Planetary Science, University of California Berkeley, Berkeley, CA, USA.
Joanne M SantiniInstitute of Structural and Molecular Biology, Division of Biosciences, University College London, London, UK.
University of California, Berkeley · USUniversity College London · GBUniversity of Bristol · GBPlanetary Science Institute · USUniversity of Cambridge · GBUniversity of Trento · ITInnovative Genomics Institute · USQuadram Institute · GBRoyal Veterinary College · GBZoological Society of London · GB

Funding

Population Genomic Analysis of Gut Microbial Colonization in Premature InfantsR01AI092531 · NIAID · UNIVERSITY OF CALIFORNIA BERKELEY · PI Jillian Banfield, Michael Morowitz · 2011 to 2026
$11.3M
Medical Research Council MR/N002660/1NIAID NIH HHS R01 AI092531
6 · The paper itself

Abstract

Lak phages with alternatively coded ∼540 kbp genomes were recently reported to replicate in

Indexed as

MicrobiomeOmicsVirology

Identifiers

PMID34386733
PMCPMC8346664
OpenAlexW3185350149

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.