ArticleKidney international reports2021
Randomized Trial-PrEscription of intraDialytic exercise to improve quAlity of Life in Patients Receiving Hemodialysis.
Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 5 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 51 citations in OpenAlex.
- Pooled it
- The effect of exercise training on quality of life in people with chronic kidney disease requiring dialysis. A systematic review with meta-analysis.Journal of nephrology · 2025Pooled it
- The effect of exercise on vascular health in chronic kidney disease: a systematic review and meta-analysis of randomized controlled trials.American journal of physiology. Renal physiology · 2023Pooled it
- Interventions for fatigue in people with kidney failure requiring dialysis.The Cochrane database of systematic reviews · 2023Pooled it
- Effect of exercise interventions for sleep quality in patients with chronic kidney disease: a systematic review and meta-analysis.International urology and nephrology · 2023Pooled it
- The effect of intradialytic resistance exercise on physical function and dialysis adequacy in patients on maintenance hemodialysis.PloS one · 2026Trial
- Comparison of the effect of aerobic and resistance training on fatigue, quality of life and biochemical factors in hemodialysis patients.Scientific reports · 2025Trial
- Exercise programme to improve quality of life for patients with end-stage kidney disease receiving haemodialysis: the PEDAL RCT.Health technology assessment (Winchester, England) · 2021Trial
- Exercise as an adjunctive therapy for patients on maintenance hemodiafiltration.Kidney research and clinical practice · 2026Article
- Using a generative co-design framework to adapt an exercise intervention as part of a multimodal intervention for patients' receiving haemodialysis with or at risk of renal cachexia.Research involvement and engagement · 2026Article
- Rehabilitation for Cardiorenal Multimorbidity: Epidemiology, Functional Phenotypes, and Effects on Physical Function, Renal Trajectory, and Prognosis.Journal of clinical medicine · 2026Review
- Characteristics, Attitudes and Preferences of an End-Stage Kidney Disease Population at the Beginning of an Exercise Program: A Pragmatic Multicenter Trial.Journal of clinical medicine · 2026Article
- Effectiveness of Physiotherapy in Haemodialysis: Systematic Review.Life (Basel, Switzerland) · 2026Review
- Type 2 Diabetes and Hemodialysis: Metabolic Challenges and the Role of Intradialytic Exercise.Clinical medicine insights. Endocrinology and diabetes · 2026Review
- Intradialytic exercise: a controlled nationwide effectiveness-implementation study.Clinical kidney journal · 2026Article
- Physical activity in kidney disease: evidence and implementation.Nature reviews. Nephrology · 2025Review
- Evidence-based practice of exercise during dialysis in maintenance hemodialysis patients.International urology and nephrology · 2025Article
- Physical activity and cardiorenal health-from associations to interventional studies.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025Review
- Impact of cycling exercise in patients with chronic kidney disease: protocol for a systematic review and trial sequential meta-analysis.Systematic reviews · 2025Article
- Factors Influencing Recruitment, Retention, and Adherence Rates in Exercise Interventions in ESKD: A Scoping Review.Kidney medicine · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
22 authors at 16 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionWhether clinically implementable exercise interventions in people receiving hemodialysis (HD) therapy improve health-related quality of life (HRQoL) remains unknown. The PrEscription of intraDialytic exercise to improve quAlity of Life
methodsIn a multicenter, single-blinded, randomized, controlled trial, people receiving HD were randomly assigned to (i) intradialytic exercise training (exercise intervention group [EX]) and (ii) usual care (control group [CON]). Primary outcome was change in Kidney Disease Quality of Life Short-Form Physical Component Summary (KDQOL-SF 1.3 PCS) from baseline to 6 months. Cost-effectiveness was determined using health economic analysis; physiological impairment was evaluated by peak oxygen uptake; and harms were recorded.
resultsWe randomized 379 participants; 335 and 243 patients (EX
conclusionsA 6-month intradialytic aerobic exercise program was not clinically beneficial in improving HRQoL as delivered to this cohort of deconditioned patients on HD.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.