ArticleJGH open : an open access journal of gastroenterology and hepatology2021
C-reactive protein predicts the development of walled-off necrosis in patients with severe acute pancreatitis.
Article in JGH open : an open access journal of gastroenterology and hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Nomogram for Predicting Pancreatic Pseudocyst in Hypertriglyceridemic Acute Pancreatitis: A Retrospective Cohort Study.Journal of inflammation research · 2026Article
- Decoding the Natural History of Alcohol-Related Recurrent Acute Pancreatitis and Progression to Early Chronic Pancreatitis: Clinical, Biochemical, and Imaging Insights from a Single-Center Retrospective Study in France.Journal of clinical medicine · 2025Article
- The Value of RANSON Score Combined with BMI in Predicting the Mortality in Severe Acute Pancreatitis: A Retrospective Study.International journal of general medicine · 2022Article
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4 authors.
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Abstract
BACKGROUND AND
aimWalled-off necrosis (WON) is reported to occur in 1-9% of patients with acute pancreatitis. However, the factors associated with the onset of this condition have not been elucidated. This study aimed to investigate the potential predictive factors for WON in patients diagnosed with severe acute pancreatitis at our hospital.
methodsThis study included 26 patients with severe acute pancreatitis identified among the 211 patients with acute pancreatitis admitted to our hospital between January 2014 and December 2018. Patients with and without WON (WON and non-WON groups, respectively) were compared to identify potential factors involved in the onset of this condition.
resultsThe 26 patients had a median age of 67 years, and 65% were male. WON occurred in 15 patients (57.7%). In a univariate analysis, the WON and non-WON groups differed significantly in terms of maximum C-reactive protein (CRP) levels (median) (322.7 mg/L vs 163.8 mg/L [
conclusionThe maximum CRP level was identified as a predictive factor for the onset of WON, and a high proportion of patients with WON exhibited elevated CRP levels within 3 days after diagnosis. This work suggests the clinical importance of continuous monitoring at an early stage after diagnosis to identify the maximum CRP level.
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