Evidence map›Paper›PMID 34386592›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2021

Consensus statements and recommendations on the management of mild-to-moderate gastroesophageal reflux disease in the Southeast Asian region.

Khean-Lee Goh, Yeong-Yeh Lee, Somchai Leelakusolvong, Dadang Makmun, Monthira Maneerattanaporn, Duc Trong Quach, Raja Affendi Raja Ali, Jose D Sollano, Van Huy Tran, Reuben Kong-Min Wong

Open access · goldAbstract read
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 24 citations in OpenAlex.

  1. Article
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  4. Review
  5. Article
  6. Observational
  7. Novel Technique to Diagnose Gastroesophageal Reflux Disease.The Korean journal of helicobacter and upper gastrointestinal research · 2024
    Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 9 institutions in 6 countries.

Khean-Lee GohDepartment of Medicine University of Malaya Kuala Lumpur Malaysia.
Yeong-Yeh LeeDepartment of Medicine, School of Medical Sciences Universiti Sains Malaysia Kota Bharu Malaysia.
Somchai LeelakusolvongDivision of Gastroenterology, Faculty of Medicine, Siriraj Hospital Mahidol University Bangkok Thailand.
Dadang MakmunDivision of Gastroenterology, Department of Internal Medicine Faculty of Medicine Universitas Indonesia/Cipto Mangunkusumo National General Hospital Jakarta Indonesia.
Monthira ManeerattanapornDivision of Gastroenterology, Faculty of Medicine, Siriraj Hospital Mahidol University Bangkok Thailand.
Duc Trong QuachDepartment of Internal Medicine University of Medicine and Pharmacy Ho Chi Minh City Vietnam.
Raja Affendi Raja AliGastroenterology Unit, Department of Medicine and Gut Research Group, Faculty of Medicine Universiti Kebangsaan Malaysia Bangi Malaysia.
Jose D SollanoDepartment of Gastroenterology University of Santo Tomas Manila Philippines.
Van Huy TranDepartment of Gastroenterology, Hue University of Medicine and Pharmacy Hue University Hue City Vietnam.
Reuben Kong-Min WongDepartment of Medicine, Faculty of Medicine National University of Singapore Singapore.
Siriraj Hospital · THHo Chi Minh City Medicine and Pharmacy University · VNHue University · VNNational University of Malaysia · MYNational University of Singapore · SGUniversiti Sains Malaysia · MYUniversity of Indonesia · IDUniversity of Malaya · MYUniversity of Santo Tomas · PH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This paper reports the proceedings from the first consensus meeting on the management of mild-to-moderate gastroesophageal reflux disease (GERD) in the Southeast Asian (SEA) region. Seventeen statements were drawn up by a steering committee that focused on epidemiology, mechanism of action, diagnostic investigations, and treatment. Voting on the recommendations used the Delphi method with two rounds of voting among the 10 panel members. The consensus panel agreed that GERD is mostly a mild disease in the SEA region with predominantly non-erosive reflux disease (NERD). Complicated GERD and Barrett's esophagus are infrequently seen. The panel recommended endoscopy in patients with alarm or refractory symptoms but cautioned that the incidence of gastric cancer is higher in SEA. pH and impedance measurements were not recommended for routine assessment. The acid pocket is recognized as an important pathogenic factor in GERD. Lifestyle measures such as weight reduction, avoidance of smoking, reduction of alcohol intake, and elevation of the head of the bed were recommended but strict avoidance of specific foods or drinks was not. Alginates was recommended as the first-line treatment for patients with mild-to-moderate GERD while recognizing that proton-pump inhibitors (PPIs) remained the mainstay of treatment of GERD. The use of alginates was also recommended as adjunctive therapy when GERD symptoms were only partially responsive to PPIs.

Indexed as

alginatesconsensus recommendationsmild‐to‐moderate gastroesophageal reflux diseaseproton‐pump inhibitors

Identifiers

PMID34386592
PMCPMC8341192
OpenAlexW3188159160

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.