Evidence map›Paper›PMID 34386463›Full record

ArticleFrontiers in pediatrics2021

Successful Treatment With Intrathecal and Intravenous Polymyxin B-Based Combination Against MDR

Haiyan Xing, Caiyi Cheng, Yihua Zhang, Yongqing Cai, Xianfeng Wang, Dongmei Deng, Lunshan Xu, Minhui Xu, Jianhong Chen

Open access · goldAbstract readCase Reports
In one paragraph

Article in Frontiers in pediatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Efficacy analysis of intraventricular/intrathecal polymyxin B sulphate injections in the treatment of Post-neurosurgical CNS infections in neurocritical ill patients: a prospective observational study.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Haiyan XingDepartment of Pharmacy, Daping Hospital, Army Medical University, Chongqing, China.
Caiyi ChengDepartment of Pharmacy, Daping Hospital, Army Medical University, Chongqing, China.
Yihua ZhangDepartment of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, China.
Yongqing CaiDepartment of Pharmacy, Daping Hospital, Army Medical University, Chongqing, China.
Xianfeng WangDepartment of Pharmacy, Daping Hospital, Army Medical University, Chongqing, China.
Dongmei DengDepartment of Pharmacy, Daping Hospital, Army Medical University, Chongqing, China.
Lunshan XuDepartment of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, China.
Minhui XuDepartment of Neurosurgery, Daping Hospital, Army Medical University, Chongqing, China.
Jianhong ChenDepartment of Pharmacy, Daping Hospital, Army Medical University, Chongqing, China.
Daping Hospital · CNArmy Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Acinetobacter baumanniiintrathecal administrationmeningitismultidrug resistancePolymyxin Btigecycline

Identifiers

PMID34386463
PMCPMC8353103
OpenAlexW3186247198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.