ArticleAsia Pacific allergy2021
Suppressive effect of dexamethasone on murine Th9 cell-mediated nasal eosinophilic inflammation.
Article in Asia Pacific allergy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Th9 and IL9 in Chronic Superior Airway Inflammation: A Narrative Review.Biomedicines · 2026Review
- Emerging Role and Function of Th9 Cells in Allergic Inflammation.Journal of inflammation research · 2025Review
- Generation of reporter mice for detecting the transcriptional activity of nuclear factor of activated T cells.Experimental animals · 2023Article
- Microbiome profiling of nasal extracellular vesicles in patients with allergic rhinitis.The World Allergy Organization journal · 2022Article
- Th17-Dependent Nasal Hyperresponsiveness Is Mitigated by Steroid Treatment.Biomolecules · 2022Article
- Preface of the Proceedings of the 34rd Workshop on Eosinophils in Allergy and Related Diseases 2020 (WEA 2020).Asia Pacific allergy · 2021Article
- Glimpses of the life journey of Prof. Sohei Makino, MD, PhD.Asia Pacific allergy · 2021Article
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundTh9 cells have been implicated in the development of allergic inflammation, though its contribution to allergic rhinitis and the effect of steroid on Th9 cell-mediated nasal responses are unclear.
objectiveIn this study, allergen-induced nasal inflammatory responses and their steroid responsiveness were investigated in ovalbumin (OVA)-specific Th9 cell-transferred mice.
methodsBALB/c mice were transferred with
resultsThe significant NHR accompanied by nasal infiltration of eosinophils as well as allergen-specific T cells was induced in Th9 cell-transferred mice upon allergen challenge. These responses were strongly suppressed by the treatment with Dex.
conclusionThe participation of Th9 cells in the pathogenesis of allergic rhinitis was suggested.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.