Evidence map›Paper›PMID 34386331›Full record

ArticleActa pharmaceutica Sinica. B2021

Coating with flexible DNA network enhanced T-cell activation and tumor killing for adoptive cell therapy.

Ziyan Zhang, Qiaojuan Liu, Jizhou Tan, Xiaoxia Zhan, Ting Liu, Yuting Wang, Gen Lu, Minhao Wu, Yuanqing Zhang

Open access · diamondAbstract read
In one paragraph

Article in Acta pharmaceutica Sinica. B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Ziyan ZhangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Qiaojuan LiuZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Jizhou TanThe First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Xiaoxia ZhanThe First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Ting LiuThe First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.
Yuting WangZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Gen LuGuangzhou Institute of Pediatrics, Guangzhou Women and Children's Medical Centre, Guangzhou Medical University, Guangzhou 510080, China.
Minhao WuZhongshan School of Medicine, Sun Yat-sen University, Guangzhou 510080, China.
Yuanqing ZhangSchool of Pharmaceutical Sciences, Sun Yat-sen University, Guangzhou 510006, China.
Sun Yat-sen University · CNGuangzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adoptive cell therapy (ACT) is an emerging powerful cancer immunotherapy, which includes a complex process of genetic modification, stimulation and expansion. During these

Indexed as

Adoptive cell therapyCell surface engineeringDNA nanostructureRolling circle amplificationSelective cytoprotectionT cellTetrahedral DNA nanostructureTumor-killing

Identifiers

PMID34386331
PMCPMC8343197
OpenAlexW3144167109

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.