Evidence map›Paper›PMID 34386232›Full record

ArticleAnnals of medicine and surgery (2012)2021

Hepatic lymphorrhea following pancreaticoduodenectomy: Preliminary diagnosis and treatment experience from case series of four patients.

Thanh Khiem Nguyen, Tuan Hiep Luong, Ngoc Cuong Nguyen, Ham Hoi Nguyen, Van Khang Le, Hong Son Trinh, Hai Dang Do, Van Duy Le, Ngoc Hung Nguyen

Open access · diamondAbstract read
In one paragraph

Article in Annals of medicine and surgery (2012), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Diagnosis and Treatment of Postoperative Hepatic Lymphorrhea.Interventional radiology (Higashimatsuyama-shi (Japan) · 2025
    Review
  3. Article
  4. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Thanh Khiem NguyenDepartment of Gastrointestinal and Hepato-pancreato-biliary Surgery, Bach Mai Hospital, Hanoi, Viet Nam.
Tuan Hiep LuongDepartment of Surgery, Hanoi Medical University, Hanoi, Viet Nam.
Ngoc Cuong NguyenDepartment of Diagnostic and Interventional Radiology, Hospital of Hanoi Medical University, Hanoi, Viet Nam.
Ham Hoi NguyenDepartment of Gastrointestinal and Hepato-pancreato-biliary Surgery, Bach Mai Hospital, Hanoi, Viet Nam.
Van Khang LeDepartment of Diagnostic and Interventional Radiology, Bach Mai Hospital, Hanoi, Viet Nam.
Hong Son TrinhDepartment of Oncology, Viet Duc University Hospital, Hanoi, Viet Nam.
Hai Dang DoDepartment of Surgery, Hanoi Medical University, Hanoi, Viet Nam.
Van Duy LeDepartment of Gastrointestinal and Hepato-pancreato-biliary Surgery, Bach Mai Hospital, Hanoi, Viet Nam.
Ngoc Hung NguyenDepartment of Gastrointestinal and Hepato-pancreato-biliary Surgery, Bach Mai Hospital, Hanoi, Viet Nam.
Bạch Mai Hospital · VNHanoi Medical University · VNViet Duc Hospital · VN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionHepatic lymphorrhea (HL) is an uncommon but potentially life-threatening type of postoperative lymphatic leakage, especially following pancreaticoduodenectomy. CASE PRESENTATION: We herein report a case series of four patients with HL following pancreaticoduodenectomy that presented to the department with a severe clinical picture with the discovery in imaging and intraperitoneal fluid's tests. All our patients presented with a condition of Hepatic lymphorrhea secondary to pancreaticoduodenectomy, which were treated successfully with percutaneous hepatic lymphangiography (HLG). DISCUSSION: Hepatic lymphorrhea is an uncommon but potentially life-threatening complication following pancreaticoduodenectomy. Periportal lymphatic vessels, which was often isolated and dissected especially with extended lymphadenectomy, is potentially damaged and caused resistant chylous leakage. Newly techniques are updated and applied in diagnosis and treatment for this difficult-to-treat complication, one of them is percutaneous Hepatic Lymphangiography (HLG).

conclusionHLG with percutaneous access could be effective to identify and terminate the chylous fistula from periportal lymphatic vessels after pancreaticoduodenectomy.

Indexed as

Case seriesExtended lymphadenectomyHepatic lymphorrheaPancreatic cancer

Identifiers

PMID34386232
PMCPMC8346360
OpenAlexW3183330174

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.