Evidence map›Paper›PMID 34386146›Full record

ArticleRadiology case reports2021

Imaging diagnosis of plexiform neurofibroma- unravelling the confounding features: A report of two cases.

Dr Shabnam Bhandari Grover, Dr Rohit Kundra, Dr Hemal Grover, Dr Vishal Gupta, Dr Rishab Gupta

Open access · goldAbstract readCase Reports
In one paragraph

Article in Radiology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.7field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. A rare case of plexiform neurofibroma.Radiology case reports · 2026
    Article
  5. Plexiform Neurofibroma Versus Parotid Tumour - A Challenge in Management.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Don't Miss the Target: A case of neurofibromatosis type 1.Sultan Qaboos University medical journal · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Dr Shabnam Bhandari GroverDepartment of Radiology, School of Medical Science and Research, Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
Dr Rohit KundraDepartment of Radiology, School of Medical Science and Research, Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
Dr Hemal GroverDepartment of Radiology, Ichan School of Medicine at Mount Sinai West, New York, USA.
Dr Vishal GuptaDepartment of Radiology, School of Medical Science and Research, Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
Dr Rishab GuptaDepartment of Radiology, School of Medical Science and Research, Sharda Hospital, Sharda University, Greater Noida, Uttar Pradesh, India.
Sharda University · INMount Sinai Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Peripheral nerve sheath tumors such as neurofibroma, comprise 5% of all benign soft tissue tumors and usually occur due to an underlying neurofibromatosis. A plexiform neurofibroma, which is a tumor occurring exclusively in neurofibromatosis1, is a rare entity and is an uncommon variant of neurofibroma. We report the clinical and imaging features of plexiform neurofibroma in two young male patients, in whom the imaging diagnosis was confirmed after biopsy. The report not only aims to highlight the characteristic imaging features of plexiform neurofibroma but we also emphasize the ultrasound appearances which are significantly characteristic and can effectively lead to the correct diagnosis at the preliminary stage of investigation. The tumors which originate from nerve sheath, are large, lobulated masses and demonstrate typical imaging features of simultaneous involvement of subcutaneous and cutaneous tissues along with infiltrative invasion of deeper structures. The tumors characteristically display fat and fluid contents and a "target sign' on evaluation by ultrasound, CT and MRI. Imaging plays an important role in confirming the diagnosis, delineating involved structures, excluding simulating conditions and forewarning a possible malignant transformation.

Indexed as

CTMRINeurofibromatosisPeripheral nerve sheath tumorPlexiform neurofibromaTarget signUltrasound

Identifiers

PMID34386146
PMCPMC8343807
OpenAlexW3186388134

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.