Evidence map›Paper›PMID 34386069›Full record

ReviewOncology letters2021

Application of natural killer cells in pancreatic cancer.

Xiaobo Peng, Ling Chen, Yuan Jiao, Yujie Wang, Zhibin Hao, Xianbao Zhan

Open access · diamondAbstract readReview
In one paragraph

Review in Oncology letters, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Innate Lymphoid Cells: Emerging Players in Pancreatic Disease.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xiaobo PengDepartment of Oncology, Changhai Hospital Affiliated to Naval Military Medical University, Shanghai 200433, P.R. China.
Ling ChenDepartment of Oncology, Changhai Hospital Affiliated to Naval Military Medical University, Shanghai 200433, P.R. China.
Yuan JiaoDepartment of Oncology, Changhai Hospital Affiliated to Naval Military Medical University, Shanghai 200433, P.R. China.
Yujie WangDepartment of Oncology, Changhai Hospital Affiliated to Naval Military Medical University, Shanghai 200433, P.R. China.
Zhibin HaoDepartment of Oncology, Changhai Hospital Affiliated to Naval Military Medical University, Shanghai 200433, P.R. China.
Xianbao ZhanDepartment of Oncology, Changhai Hospital Affiliated to Naval Military Medical University, Shanghai 200433, P.R. China.
Second Military Medical University · CNChanghai Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pancreatic cancer, a highly malignant disease, is characterized by rapid progression and early metastasis. Although the integrative treatment of pancreatic cancer has made great progress, the prognosis of patients with advanced pancreatic cancer remains extremely poor. In recent years, with the advancements in tumor immunology, immunotherapy has become a promising remedy for pancreatic cancer. Natural killer (NK) cells are the key lymphocytes in the innate immune system. NK cell function does not require antigen pre-sensitization and is not major histocompatibility complex restricted. By targeting tumors or virus-infected cells, the cells play a key role in immune surveillance. Although several questions about NK cells in pancreatic cancer still need to be further studied, there are extensive theories supporting the clinical application prospects of NK cell immunotherapy in pancreatic cancer. Since very few studies have evaluated the role of NK cells in pancreatic cancer, this review provides a comprehensive update of the role of NK cells in pancreatic cancer immunotherapy.

Indexed as

immunotherapynatural killer cellnatural killer group 2Dpancreatic cancer

Identifiers

PMID34386069
PMCPMC8299011
OpenAlexW3178752761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.