Evidence map›Paper›PMID 34385920›Full record

ArticleFrontiers in pharmacology2021

Antiatherogenic Effects of Quercetin in the THP-1 Macrophage Model

Etimad A Huwait, Salma Y Saddeek, Rehab F Al-Massabi, Sanaa J Almowallad, Peter Natesan Pushparaj, Gauthaman Kalamegam

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Review of OxLDL Driven Inflammatory Cell Activation.Current atherosclerosis reports · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Etimad A HuwaitBiochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Salma Y SaddeekBiochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Rehab F Al-MassabiBiochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Sanaa J AlmowalladBiochemistry Department, Faculty of Sciences, King Abdulaziz University, Jeddah, Saudi Arabia.
Peter Natesan PushparajCenter of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia.
Gauthaman KalamegamCenter of Excellence in Genomic Medicine Research, King Abdulaziz University, Jeddah, Saudi Arabia.
King Abdulaziz University · SAUniversity of Tabuk · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

atherosclerosisbrain destructioncell migrationinflammmationingenuity pathway analysisstrokeSwissTargetPredictionTHP-1 macrophages

Identifiers

PMID34385920
PMCPMC8353397
OpenAlexW3183676203

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.