Evidence map›Paper›PMID 34385907›Full record

ArticleFrontiers in molecular neuroscience2021

The Potential Effect of Na

Björn Heinrichs, Baowen Liu, Jin Zhang, Jannis E Meents, Kim Le, Andelain Erickson, Petra Hautvast, Xiwen Zhu, Ningbo Li, Yi Liu and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 7 institutions in 2 countries.

Björn HeinrichsInstitute of Physiology, Uniklinik RWTH Aachen University, Aachen, Germany.
Baowen LiuDepartment of Anesthesiology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Jin ZhangDepartment of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Jannis E MeentsInstitute of Physiology, Uniklinik RWTH Aachen University, Aachen, Germany.
Kim LeDepartment of Chemosensation, AG Neuromodulation, Institute for Biology II, RWTH Aachen University, Aachen, Germany.
Andelain EricksonInstitute of Physiology, Uniklinik RWTH Aachen University, Aachen, Germany.
Petra HautvastInstitute of Physiology, Uniklinik RWTH Aachen University, Aachen, Germany.
Xiwen ZhuDepartment of Anesthesiology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
Ningbo LiDepartment of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Yi LiuInstitute of Physiology, Uniklinik RWTH Aachen University, Aachen, Germany.
Marc SpehrDepartment of Chemosensation, Institute for Biology II, RWTH Aachen University, Aachen, Germany.
Ute HabelDepartment of Psychiatry, Psychotherapy and Psychosomatics, Uniklinik RWTH Aachen University, Aachen, Germany.
Markus RothermelInstitute for Physiology and Cell Biology, University of Veterinary Medicine, Foundation, Hanover, Germany.
Barbara NamerResearch Group Neurosciences of the Interdisciplinary Center for Clinical Research (IZKF), Faculty of Medicine, RWTH Aachen University, Aachen, Germany.
Xianwei ZhangDepartment of Anesthesiology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Angelika LampertInstitute of Physiology, Uniklinik RWTH Aachen University, Aachen, Germany.
Guangyou DuanDepartment of Anesthesiology, The Second Affiliated Hospital, Chongqing Medical University, Chongqing, China.
RWTH Aachen University · DEDalian Medical University · CNUniversitätsklinikum Aachen · DETongji Hospital · CNBrain (Germany) · DEHuazhong University of Science and Technology · CNUniversity of Veterinary Medicine Hannover, Foundation · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Apart from the most prominent symptoms in Autism spectrum disorder (ASD), namely deficits in social interaction, communication and repetitive behavior, patients often show abnormal sensory reactivity to environmental stimuli. Especially potentially painful stimuli are reported to be experienced in a different way compared to healthy persons. In our present study, we identified an ASD patient carrying compound heterozygous mutations in the voltage-gated sodium channel (VGSC) Na

Indexed as

autism spectrum disordergeneticmutationp.I1511Mp.R512∗SCN10A/Nav1.8

Identifiers

PMID34385907
PMCPMC8354588
OpenAlexW3119786213

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.