Trial reportDiabetes, metabolic syndrome and obesity : targets and therapy2021
Effects of Short-Term Dietary Fiber Intervention on Gut Microbiota in Young Healthy People.
Trial report in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 47 citations in OpenAlex.
- Gut microbes and immunotherapy for non-small cell lung cancer: a systematic review.Frontiers in oncology · 2025Pooled it
- Targeting gut microbiota with short-chain fructo-oligosaccharides prebiotic fibers to support metabolic health in overweight prediabetic adults: a randomized, double-blinded, placebo-controlled study.Frontiers in nutrition · 2025Trial
- Trial
- Trial
- Modulatory role of Akkermansia muciniphila in cancer pathophysiology: a systematic review and meta-analysis of preclinical studies.Gut pathogens · 2026Review
- Grape Exosome-Like Nanovesicles Reverse the Prediabetic State in Mice.Journal of diabetes research · 2026Article
- Impact of data compositionality on the detection of microbiota responses.Gut microbes · 2025Article
- A Comprehensive Review of the Triangular Relationship Among Diet, Gut Microbiota, and Aging.International journal of molecular sciences · 2025Review
- Totum-448 Improves MASLD and Modulates Microbiota in Hamsters: Dose-Response Study and Effects of Supplementation Cessation.Food science & nutrition · 2025Article
- Postbiotic Parabacteroides Distasonis Supplementation Enhances Intestinal and Skeletal Muscle Function in Aged Mice.Aging and disease · 2025Article
- Exploring the relationship between ultra-processed food consumption and gut microbiota at school age in a Brazilian birth cohort.Cadernos de saude publica · 2025Article
- Deconstruct the link between gut microbiota and neurological diseases: application of Mendelian randomization analysis.Frontiers in cellular and infection microbiology · 2025Review
- Unraveling the Gut Microbiota: Implications for Precision Nutrition and Personalized Medicine.Nutrients · 2024Review
- Changes in the Human Gut Microbiome Caused by the Short-Term Impact of Lactic Acid Bacteria Consumption in Healthy People.Probiotics and antimicrobial proteins · 2024Article
- Association between Circulating T Cells and the Gut Microbiome in Healthy Individuals: Findings from a Pilot Study.International journal of molecular sciences · 2024Article
- Short-term dietary fiber interventions produce consistent gut microbiome responses across studies.mSystems · 2024Article
- Nonalcoholic Fatty Liver Disease: Changes in Gut Microbiota and Blood Lipids.Journal of clinical and translational hepatology · 2024Article
- Modulation of gut microbiome in response to the combination ofFrontiers in nutrition · 2024Article
- Health-associated changes of the fecal microbiota in dairy heifer calves during the pre-weaning period.Frontiers in microbiology · 2024Article
- Effects of Soluble Dietary Fibre on Exercise Performance and Perception of Fatigue in Young Basketball Players.Food technology and biotechnology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Gut microbiota are critical to many aspects of human health including immune and metabolic health. Long-term diet influences the community structure and activity of the trillions of microorganisms residing in the human gut, but it remains unclear how the human gut microbiome responds to short-term intervention with dietary fiber. This study explored the effects of mixed dietary fibers on gut microbiota in young, healthy people. Twelve healthy, young adults participated in a randomized, crossover trial comparing the effects of polyglucan, inulin and resistant malt dextrin on gut microbiota composition and bacterial abundances. During the study, the subjects followed their normal diets without any constraints. Microbial community profiles were determined by absolute quantification 16S rRNA gene amplicon sequencing. Mixed model analysis did not reveal an effect of dietary intervention on microbial community structure. At the genus level, dietary fiber intervention for 4 days significantly promoted the growth of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.