ArticleJournal of perinatology : official journal of the California Perinatal Association2021
Hydrops fetalis-trends in associated diagnoses and mortality from 1997-2018.
Article in Journal of perinatology : official journal of the California Perinatal Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Complex congenital heart and lung defects as a cause of hydrops fetalis in French bulldogs -micro-CT with contrast study.Scientific reports · 2025Article
- Hydrops and congenital diaphragmatic hernia: reported incidence and postnatal outcomes. Analysis of the congenital diaphragmatic hernia study group registry.Journal of perinatology : official journal of the California Perinatal Association · 2024Article
- Hydrops fetalis caused by a complex congenital heart defect with concurrent hypoplasia of pulmonary blood vessels and lungs visualized by micro-CT in a French Bulldog.BMC veterinary research · 2024Article
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Authors and funding
8 authors.
Funding
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Abstract
objectivesTo describe and evaluate trends in the etiology and mortality risk in neonates admitted for neonatal intensive care with hydrops fetalis. STUDY
designA retrospective review of de-identified patient data in the Pediatrix Clinical Data Warehouse from 1997 to 2018.
resultsWe identified 2144 infants diagnosed with hydrops fetalis. The most common diagnoses were congenital heart disease (n = 325, 15.2%), genetic diagnoses (n = 269, 12.5%) and cardiac arrhythmia (n = 176, 8.2%). Of 2144 neonates, 988 (46%) survived to hospital discharge and 775 (36%) died prior to discharge. Mortality rate was highly variable across diagnoses, ranging from 90% in infants with congenital diaphragmatic hernia to 0% in infants with atrial flutter. Over the study period, more infants were diagnosed with trisomies and fewer with twin-to-twin transfusion. Mortality decreased by 5% from 1997-2007 to 2008-2018.
conclusionsThe risk of death among neonates with hydrops fetalis is highly dependent on the underlying cause, with increasing risk of mortality at lower gestational ages.
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