ArticleScientific reports2021
Metabolic signatures in the conversion from gestational diabetes mellitus to postpartum abnormal glucose metabolism: a pilot study in Asian women.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 23 citations in OpenAlex.
- The association of serum total bile acid levels with gestational diabetes mellitus: a systematic review and meta-analysis.BMC pregnancy and childbirth · 2024Pooled it
- Models Predicting Postpartum Glucose Intolerance Among Women with a History of Gestational Diabetes Mellitus: a Systematic Review.Current diabetes reports · 2023Pooled it
- Impact of Olive Oil Components on the Expression of Genes Related to Type 2 Diabetes Mellitus.Nutrients · 2025Review
- Risk prediction models for postpartum glucose intolerance in women with a history of gestational diabetes mellitus: a scoping review.Journal of diabetes and metabolic disorders · 2024Article
- The role of lipid dysregulation in gestational diabetes mellitus: Early prediction and postpartum prognosis.Journal of diabetes investigation · 2024Review
- Association between serum free fatty acids and gestational diabetes mellitus.Frontiers in endocrinology · 2024Article
- Exploring preconception signatures of metabolites in mothers with gestational diabetes mellitus using a non-targeted approach.BMC medicine · 2023Article
- Effect of Resveratrol on Pregnancy, Prenatal Complications and Pregnancy-Associated Structure Alterations.Antioxidants (Basel, Switzerland) · 2023Review
- Causal relationship between linoleic acid and type 2 diabetes and glycemic traits: a bidirectional Mendelian randomization study.Frontiers in endocrinology · 2023Article
- Gestational Diabetes Mellitus with autoimmune subclinical hypothyroidism in pregnancy in relation to gravida.Journal of family medicine and primary care · 2022Article
- Polyunsaturated fatty acid intake and incidence of type 2 diabetes in adults: a dose response meta-analysis of cohort studies.Diabetology & metabolic syndrome · 2022Article
- The Effect of Resveratrol on Blood Glucose and Blood Lipids in Rats with Gestational Diabetes Mellitus.Evidence-based complementary and alternative medicine : eCAM · 2021Article
Corrections and comments
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Authors and funding
9 authors at 8 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We aimed to identify serum metabolites related to abnormal glucose metabolism (AGM) among women with gestational diabetes mellitus (GDM). The study recruited 50 women diagnosed with GDM during mid-late pregnancy and 50 non-GDM matchees in a Singapore birth cohort. At the 5-year post-partum follow-up, we applied an untargeted approach to investigate the profiles of serum metabolites among all participants. We first employed OPLS-DA and logistic regression to discriminate women with and without follow-up AGM, and then applied area under the curve (AUC) to assess the incremental indicative value of metabolic signatures on AGM. We identified 23 candidate metabolites that were associated with postpartum AGM among all participants. We then narrowed down to five metabolites [p-cresol sulfate, linoleic acid, glycocholic acid, lysoPC(16:1) and lysoPC(20:3)] specifically associating with both GDM and postpartum AGM. The combined metabolites in addition to traditional risks showed a higher indicative value in AUC (0.92-0.94 vs. 0.74 of traditional risks and 0.77 of baseline diagnostic biomarkers) and R
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