Evidence map›Paper›PMID 34385472›Full record

ReviewNPJ Regenerative medicine2021

Cellularized small-caliber tissue-engineered vascular grafts: looking for the ultimate gold standard.

Adrien Fayon, Patrick Menu, Reine El Omar

Abstract readReview
In one paragraph

Review in NPJ Regenerative medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  12. Optimization and Standardization of Plant-Derived Vascular Scaffolds.International journal of molecular sciences · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Adrien FayonUniversité de Lorraine, CNRS, IMoPA, F-54000 Nancy, France.ORCID http://orcid.org/0000-0002-6025-5756
Patrick MenuUniversité de Lorraine, CNRS, IMoPA, F-54000 Nancy, France. patrick.menu@univ-lorraine.fr.ORCID http://orcid.org/0000-0001-6428-7475
Reine El OmarUniversité de Lorraine, CNRS, IMoPA, F-54000 Nancy, France.ORCID http://orcid.org/0000-0002-8984-2022

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Due to the lack of efficacy of synthetic vascular substitutes in the replacement of small-caliber arteries, vascular tissue engineering (VTE) has emerged as a promising solution to produce viable small-caliber tissue-engineered vascular grafts (TEVG). Previous studies have shown the importance of a cellular intimal layer at the luminal surface of TEVG to prevent thrombotic events. However, the cellularization of a TEVG seems to be a critical approach to consider in the development of a TEVG. To date, no standard cellularization method or cell type has been established to create the ideal TEVG by promoting its long-term patency and function. In this review, advances in VTE are described and discussed with a particular focus on the construction approaches of cellularized small-caliber TEVGs, the cell types used, as well as their preclinical and clinical applications.

Identifiers

PMID34385472
PMCPMC8361171

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.