ArticleNature communications2021
Rational design of pyrrole derivatives with aggregation-induced phosphorescence characteristics for time-resolved and two-photon luminescence imaging.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Mechanical flexibility and pressure-activated emission in room-temperature phosphorescent organic crystals.Nature communications · 2026Article
- Photo-Responsive Organic RTP of Benzothiophene Derivative.Chemistry, an Asian journal · 2026Article
- Recent Advances of Organic Room Temperature Phosphorescence for Biological Applications.Advanced materials (Deerfield Beach, Fla.) · 2026Review
- Folate-Targeted Liposomal Delivery of a Ru(II)-Based Photosensitizer for Photodynamic Tumor Therapy via Pyroptosis Induction.Advanced healthcare materials · 2026Article
- Breaking Kasha's rule for photoswitchable reactive oxygen species generation in carbonylated carbon nitride.National science review · 2025Article
- White light-excited organic room-temperature phosphorescence for improved in vivo bioimaging.Nature communications · 2025Article
- Regulating Triplet Excitons of Organic Luminophores for Promoted Bioimaging.Current medicinal chemistry · 2025Review
- Preparation of AIEgen-based near-infrared afterglow luminescence nanoprobes for tumor imaging and image-guided tumor resection.Nature protocols · 2024Review
- SynergisticChemical science · 2024Article
- Exploring and Anticipating the Applications of Organic Room-Temperature Phosphorescent Materials in Biomedicine and Dentistry.International journal of nanomedicine · 2024Review
- The Bioimaging Story of AIEgens.Chemical & biomedical imaging · 2023Review
- A functional unit combination strategy for enhancing red room-temperature phosphorescence.Chemical science · 2023Article
- Durable organic nonlinear optical membranes for thermotolerant lightings and in vivo bioimaging.Nature communications · 2023Article
- Lighting up metastasis process before formation of secondary tumor by phosphorescence imaging.Science advances · 2023Article
- Oxidization enhances type I ROS generation of AIE-active zwitterionic photosensitizers for photodynamic killing of drug-resistant bacteria.Chemical science · 2023Article
- Photoactivated organic phosphorescence by stereo-hindrance engineering for mimicking synaptic plasticity.Light, science & applications · 2023Article
- Room-Temperature Phosphorescence and Cellular Phototoxicity Activated by Triplet Dynamics in Aggregates of Push-Pull Phenothiazine-Based Isomers.The journal of physical chemistry. B · 2023Article
- Organic persistent luminescence imaging for biomedical applications.Materials today. Bio · 2022Article
- NIR-II AIEgens with Photodynamic Effect for Advanced Theranostics.Molecules (Basel, Switzerland) · 2022Review
- Organic phosphorescent nanoscintillator for low-dose X-ray-induced photodynamic therapy.Nature communications · 2022Article
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Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pure organic room-temperature phosphorescent (RTP) materials have been suggested to be promising bioimaging materials due to their good biocompatibility and long emission lifetime. Herein, we report a class of RTP materials. These materials are developed through the simple introduction of an aromatic carbonyl to a tetraphenylpyrrole molecule and also exhibit aggregation-induced emission (AIE) properties. These molecules show non-emission in solution and purely phosphorescent emission in the aggregated state, which are desirable properties for biological imaging. Highly crystalline nanoparticles can be easily fabricated with a long emission lifetime (20 μs), which eliminate background fluorescence interference from cells and tissues. The prepared nanoparticles demonstrate two-photon absorption characteristics and can be excited by near infrared (NIR) light, making them promising materials for deep-tissue optical imaging. This integrated aggregation-induced phosphorescence (AIP) strategy diversifies the existing pool of bioimaging agents to inspire the development of bioprobes in the future.
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