Evidence map›Paper›PMID 34385444›Full record

ArticleNature communications2021

Ultra-conformal skin electrodes with synergistically enhanced conductivity for long-time and low-motion artifact epidermal electrophysiology.

Yan Zhao, Song Zhang, Tianhao Yu, Yan Zhang, Guo Ye, Han Cui, Chengzhi He, Wenchao Jiang, Yu Zhai, Chunming Lu and 2 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed, 1 pooled it
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 1 synthesis or guideline pooled it, 286 citations in OpenAlex.

  1. Pooled it
  2. Designing PEDOT:PSS hydrogels for bioelectronic interfaces.Materials today (Kidlington, England) · 2026
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  17. Antifouling All-Polymeric Microneedle Array for Long-Term Wearable ECG Monitoring.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  18. Hundred-Nanometer-Thick Stretchable Liquid Metal Films for Ultra-Conformal Bioelectrodes.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  19. Organic Electrochemical Transistors in Tissue-Interfaced Bioelectronics.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Review
  20. Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Yan ZhaoBeijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, China.
Song ZhangSchool of Polymer Science and Engineering, The University of Southern Mississippi, Center for Optoelectronic Materials and Device, Hattiesburg, MS, USA.ORCID 0000-0001-9815-7046
Tianhao YuBeijing Graphene Institute, Beijing, China.ORCID 0000-0001-9637-352X
Yan ZhangBeijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, China.
Guo YeBeijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, China.
Han CuiDepartment of Acupuncture and Moxibustion, Shenzhen Traditional Chinese Medicine Hospital, Shenzhen, China.
Chengzhi HeBeijing Advanced Innovation Center for Soft Matter Science and Engineering, Beijing University of Chemical Technology, Beijing, China.ORCID 0000-0001-5013-0207
Wenchao JiangBeijing Graphene Institute, Beijing, China.
Yu ZhaiState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.
Chunming LuState Key Laboratory of Cognitive Neuroscience and Learning & IDG/McGovern Institute for Brain Research, Beijing Normal University, Beijing, China.ORCID 0000-0002-0040-0587
Xiaodan GuSchool of Polymer Science and Engineering, The University of Southern Mississippi, Center for Optoelectronic Materials and Device, Hattiesburg, MS, USA.ORCID 0000-0002-1123-3673
Nan LiuBeijing Key Laboratory of Energy Conversion and Storage Materials, College of Chemistry, Beijing Normal University, Beijing, China. nanliu@bnu.edu.cn.ORCID 0000-0002-1793-7372
Beijing Normal University · CNBeijing Graphene Institute · CNUniversity of Southern Mississippi · USBeijing University of Chemical Technology · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate and imperceptible monitoring of electrophysiological signals is of primary importance for wearable healthcare. Stiff and bulky pregelled electrodes are now commonly used in clinical diagnosis, causing severe discomfort to users for long-time using as well as artifact signals in motion. Here, we report a ~100 nm ultra-thin dry epidermal electrode that is able to conformably adhere to skin and accurately measure electrophysiological signals. It showed low sheet resistance (~24 Ω/sq, 4142 S/cm), high transparency, and mechano-electrical stability. The enhanced optoelectronic performance was due to the synergistic effect between graphene and poly (3,4-ethylenedioxythiophene) polystyrene sulfonate (PEDOT:PSS), which induced a high degree of molecular ordering on PEDOT and charge transfer on graphene by strong π-π interaction. Together with ultra-thin nature, this dry epidermal electrode is able to accurately monitor electrophysiological signals such as facial skin and brain activity with low-motion artifact, enabling human-machine interfacing and long-time mental/physical health monitoring.

Indexed as

ElectrodesWearable Electronic DevicesArtifactsBridged Bicyclo Compounds, HeterocyclicElectric ConductivityElectrophysiologyEpidermisEquipment DesignGraphiteHumansMolecular StructureMonitoring, PhysiologicMotionPolymersPolystyrenesSkinBridged Bicyclo Compounds, HeterocyclicGraphitepoly(3,4-ethylene dioxythiophene)PolymersPolystyrenespolystyrene sulfonic acid

Identifiers

PMID34385444
PMCPMC8361161
OpenAlexW3119012617

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.