Evidence map›Paper›PMID 34385249›Full record

ArticleBMJ open2021

Opioid analgesic use after ambulatory surgery: a descriptive prospective cohort study of factors associated with quantities prescribed and consumed.

Christopher W Shanahan, Olivia Reding, Inga Holmdahl, Julia Keosaian, Ziming Xuan, David McAneny, Marc Larochelle, Jane Liebschutz

Abstract read
In one paragraph

Article in BMJ open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Christopher W ShanahanSection of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA christopher.shanahan@bmc.org.ORCID 0000-0001-9067-5922
Olivia RedingSection of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0001-5926-384X
Inga HolmdahlSection of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.
Julia KeosaianSection of General Internal Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0002-7138-1950
Ziming XuanCommunity Health Sciences, Boston University, Boston, Massachusetts, USA.ORCID 0000-0001-6139-4785
David McAnenyDepartment of General Surgery, Boston University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0002-6405-0424
Marc LarochelleDepartment of Medicine, Boston University School of Medicine, Boston, Massachusetts, USA.ORCID 0000-0001-7344-1200
Jane LiebschutzDivision of General Internal Medicine, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA.ORCID 0000-0003-3492-1521

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo prospectively characterise: (1) postoperative opioid analgesic prescribing practices; (2) experience of patients undergoing elective ambulatory surgeries and (3) impact of patient risk for medication misuse on postoperative pain management.

designLongitudinal survey of patients 7 days before and 7-14 days after surgery.

settingAcademic urban safety-net hospital.

participants181 participants recruited, 18 surgeons, follow-up data from 149 participants (82% retention); 54% women; mean age: 49 years.

interventionsNone. PRIMARY AND SECONDARY OUTCOME MEASURES: Total morphine equivalent dose (MED) prescribed and consumed, percentage of unused opioids.

resultsSurgeons postoperatively prescribed a mean of 242 total MED per patient, equivalent to 32 oxycodone (5 mg) pills. Participants used a mean of 116 MEDs (48%), equivalent to 18 oxycodone (5 mg) pills (~145 mg of oxycodone remaining per patient). A 10-year increase in patient age was associated with 12 (95% CI (-2.05 to -0.35)) total MED fewer prescribed opioids. Each one-point increase in the preoperative Graded Chronic Pain Scale was associated with an 18 (6.84 to 29.60) total MED increase in opioid consumption, and 5% (-0.09% to -0.005%) fewer unused opioids. Prior opioid prescription was associated with a 55 (5.38 to -104.82) total MED increase in opioid consumption, and 19% (-0.35% to -0.02%) fewer unused opioids. High-risk drug use was associated with 9% (-0.19% to 0.002%) fewer unused opioids. Pain severity in previous 3 months, high-risk alcohol, use and prior opioid prescription were not associated with postoperative prescribing practices.

conclusionsParticipants with a preoperative history of chronic pain, prior opioid prescription, and high-risk drug use were more likely to consume higher amounts of opioid medications postoperatively. Additionally, surgeons did not incorporate key patient-level factors (eg, substance use, preoperative pain) into opioid prescribing practices. Opportunities to improve postoperative opioid prescribing include system changes among surgical specialties, and patient education and monitoring.

Indexed as

Ambulatory Surgical ProceduresAnalgesics, OpioidFemaleHumansMaleMiddle AgedPostoperative PainPractice Patterns, Physicians'Prospective StudiesAnalgesics, Opioidgeneral medicine (see Internal Medicine)pain managementpublic healthsubstance misusesurgery

Identifiers

PMID34385249
PMCPMC8362709

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.