Evidence map›Paper›PMID 34384705›Full record

ArticleThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2022

The Link Between Depressive Symptoms and Vaping Nicotine in U.S. Adolescents, 2017-2019.

Lauren Gorfinkel, Deborah Hasin, Richard Miech, Katherine M Keyes

Open access · greenAbstract read
In one paragraph

Article in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Guideline
  2. Pooled it
  3. Article
  4. Associations Between County-Level Vape-Free Air Law Coverage and E-Cigarette Use Behaviors Among U.S. Adolescents in Monitoring the Future.The Journal of adolescent health : official publication of the Society for Adolescent Medicine · 2026
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  11. Psychological Distress and Cannabis Vaping Among U.S. Adolescents.American journal of preventive medicine · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Lauren GorfinkelDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada; New York State Psychiatric Institute, New York, New York. Electronic address: lrgorfinkel@gmail.com.
Deborah HasinNew York State Psychiatric Institute, New York, New York; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York; Department of Psychiatry, College of Physicians and Surgeons, Columbia University, New York, New York.
Richard MiechInstitute for Social Research, University of Michigan, Ann Arbor, Michigan.
Katherine M KeyesDepartment of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York.
New York State Psychiatric InstituteColumbia University · USUniversity of Michigan · US

Funding

As adolescent substance use declines, internalizing symptoms increase: identifying high-risk substance using groups and the role of social media, parental supervision, and unsupervised timeR01DA048853 · NIDA · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KEYES, KATHERINE M. · 2019 to 2023
$2.0M
NIDA NIH HHS R01 DA048853
6 · The paper itself

Abstract

purposeWhile there is a well-established association between depression and cigarette use, the mental health sequelae of vaping nicotine remain unclear. This study examined whether adolescents with depressive symptoms had higher odds of vaping nicotine than others, and how this association differed when examining vaping with cigarette use, vaping without cigarette use, and cigarette use alone.

methodsUsing 2017-2019 Monitoring the Future data, we examined U.S. adolescents in the eighth, 10th and 12th grades surveyed in schools across the contiguous states. Depressive symptoms were measured by using questions around negative affect and hopelessness. The outcome included vaping with cigarette use; vaping without cigarette use; cigarette use alone; and neither. Control covariates included sex, race, highest level of parental education, and average grades.

resultsThe sample included 32,636 adolescents. Depressive symptoms were positively associated with comorbid vaping and cigarette use across all grades (eighth graders: adjusted odds ratio [aOR] = 3.52 [95% confidence interval (CI): 1.94-6.39]; 10th graders: aOR = 2.26 [95% CI: 1.51-3.38]; 12th graders: aOR = 1.81 [95% CI: 1.05-3.12]); vaping without cigarette use among eighth graders (eighth graders: aOR = 2.01 [95% CI: 1.46-2.77]; 10th graders: aOR = 1.20 [95% CI: .97-1.49]; 12th graders: aOR = 1.20 [95% CI: .84-1.70]); and cigarette use alone among eighth and 10th graders (eighth graders: aOR = 2.91 [95% CI: 1.50-5.62]; 10th graders: aOR = 2.29 [95% CI: 1.35-3.88]; 12th graders: aOR = 1.73 [95% CI: .83-3.61]).

conclusionsEighth grade adolescents with depressive symptoms have increased odds of vaping nicotine with and without cigarette use. As vaping prevalence increases, clinician assessment of adolescent vaping should concomitantly acknowledge potential mental health correlates. Vaping may be a marker for a broader constellation of adolescent health concerns, including mental health.

Indexed as

Electronic Nicotine Delivery SystemsTobacco ProductsVapingAdolescentDepressionHumansNicotineNicotineAdolescent mental healthCigarettesDepressionNicotineVaping

Identifiers

PMID34384705
PMCPMC12366144
OpenAlexW3192671907

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.