SynthesisSystematic reviews2021
Sero-prevalence of syphilis and associated factors among pregnant women in Ethiopia: a systematic review and meta-analysis.
Synthesis in Systematic reviews, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Seroprevalence of human immunodeficiency virus in African blood donors: a systematic review and meta-analysis.EBioMedicine · 2024Pooled it
- Seroprevalence of Syphilis Among Pregnant Women on Antenatal Care Service at Wereda 04 Health Center in Kolfe Keraniyo Subcity, Addis Ababa, Ethiopia: A Cross-Sectional Study.Health science reports · 2026Article
- Prevalence and risk factors of hepatitis B, hepatitis C, and syphilis among reproductive-age adults in the Tigray region, Northern Ethiopia: a community-based cross-sectional study.Scientific reports · 2026Article
- Prevalence and correlates of active syphilis diagnosed using serological assays and the molecular research-use-only AptimaFrontiers in public health · 2026Article
- Prevalence and associated factors of sexually transmitted infections among pregnant women attending antenatal care in public hospitals in Addis Ababa, Ethiopia.BMC infectious diseases · 2025Article
- Seroprevalence of syphilis and associated factors among pregnant women who attended antenatal care follow-up at public hospitals in Bahir Dar city, north-west Ethiopia: a cross-sectional study.BMJ public health · 2025Article
- Sero-prevalence of syphilis and associated risk factors among pregnant women attending antenatal care at an urban-poor health centre in Kampala, Uganda: a cross-sectional study.The Pan African medical journal · 2024Article
- Sero-prevalence and associated factors of sexually transmitted infections among youth-friendly services Attendees.PloS one · 2023Article
- Magnitudes and Correlates of Human Immunodeficiency Virus, Hepatitis B Virus, and Syphilis among Pregnant Mothers Attending Antenatal Care in Addis Ababa, Ethiopia.Infectious diseases in obstetrics and gynecology · 2022Article
- Why Syphilis Infection is High Among Pregnant Women in Refugee Camps? A Case in Ethiopia.International journal of women's health · 2022Article
Corrections and comments
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Authors and funding
2 authors.
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Abstract
backgroundSyphilis remained a major cause of reproductive morbidity and poor pregnancy outcomes in developing countries. Previously, studies showed inconsistent results and failed to show the actual picture of the diseases in Ethiopia. Thus, the aim of this meta-analysis was, first, to determine the updated pooled prevalence of syphilis among pregnant women in Ethiopia and, second, to assess its associated factors.
methodsA comprehensive search was made on PubMed, Google scholar, Science Direct, and African Journals Online databases to identify relevant articles. A random effects model was used to estimate pooled syphilis prevalence and odds ratio (OR) with the respective 95% confidence intervals (CIs) using STATA 14 statistical software. I
resultWe identified 13 suitable studies in this analysis. Accordingly, the pooled prevalence of syphilis among pregnant women in Ethiopia was 2.32% (95% CI, 1.68-2.97). Specifically, syphilis prevalence was 2.53% (95% CI, 1.92-3.14%) and 1.90% (95% CI, 0.40-3.40%) as per the treponemal and non-ytreponemal diagnostic test, respectively. On the other hand, regional analysis indicated that 4.06% (95% CI, 2.86-5.26) in Southern Nations Nationalities and Peoples (SNNP), 2.16% (95% CI, 1.57-2.75) in Amhara and 1.46% (95% CI, 0.69-2.23) in Oromia region. Being married (OR, 0.37 (95% CI, 0.12-0.91%)) was less likely to develop syphilis. On the other hand, women with history of multiple sexual partner (OR, 2.98 (95% CI, 1.15-7.70)) and women with history of previous sexually transmitted infection (STI) (OR, 4.88 (95% CI, 1.35-17.62)) have higher risk to develop syphilis. Besides, the pooled syphilis-HIV coinfection was 0.80% (95% CI, 0.60-1.01%).
conclusionThis study provides evidence of relatively high prevalence of syphilis among pregnant women in Ethiopia. Therefore, it is recommended to further ramping up of current intervention measures to prevent future generations. SYSTEMATIC REVIEW REGISTRATION: PROSPERO CRD42020211650.
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