Evidence map›Paper›PMID 34384467›Full record

ArticleMolecular brain2021

TPEN attenuates amyloid-β

Wen-Bo Chen, Yu-Xiang Wang, Hong-Gang Wang, Di An, Dan Sun, Pan Li, Tao Zhang, Wan-Ge Lu, Yan-Qiang Liu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular brain, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Role of TPEN in Amyloid-βMolecular neurobiology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wen-Bo ChenCollege of Life Sciences, Nankai University, Tianjin, 300071, People's Republic of China.
Yu-Xiang WangDepartment of Immunology and Pathogenic Biology, School of Basic Medical Sciences, Hebei University of Chinese Medicine, Shijiazhuang, 050200, Hebei, People's Republic of China.
Hong-Gang WangCollege of Life Sciences, Nankai University, Tianjin, 300071, People's Republic of China.
Di AnCollege of Life Sciences, Nankai University, Tianjin, 300071, People's Republic of China.
Dan SunCollege of Life Sciences, Nankai University, Tianjin, 300071, People's Republic of China.
Pan LiTianjin Key Laboratory of Cerebral Vascular and Neurodegenerative Diseases, Tianjin Neurosurgery Institute, Department of Neurology, Tianjin Huanhu Hospital Affiliated to Nankai University, Tianjin, People's Republic of China.
Tao ZhangCollege of Life Sciences, Nankai University, Tianjin, 300071, People's Republic of China.
Wan-Ge LuCollege of Life Sciences, Nankai University, Tianjin, 300071, People's Republic of China.
Yan-Qiang LiuCollege of Life Sciences, Nankai University, Tianjin, 300071, People's Republic of China. liuyanq@nankai.edu.cn.ORCID 0000-0003-4296-728X

Funding

National Natural Science Foundation of China 31272317
6 · The paper itself

Abstract

To understand the role of intracellular zinc ion (Zn

Indexed as

Action PotentialsAmyloid beta-PeptidesAnimalsCells, CulturedEthylenediaminesFemaleHippocampusIon Channel GatingMaleNerve Tissue ProteinsNeuronsPatch-Clamp TechniquesPeptide FragmentsPotassium Channels, Voltage-GatedRatsSingle-Cell AnalysisAmyloid beta-Peptidesamyloid beta-protein (25-35)EthylenediaminesNerve Tissue ProteinsN,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediaminePeptide FragmentsPotassium Channels, Voltage-GatedVoltage-Gated Sodium ChannelsZincAβ25–35Channel currentsTPENVoltage-gated potassium channelsVoltage-gated sodium channelsZinc ions

Identifiers

PMID34384467
PMCPMC8359616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.