Evidence map›Paper›PMID 34384446›Full record

ArticleJournal of nanobiotechnology2021

Development of an anti-infective coating on the surface of intraosseous implants responsive to enzymes and bacteria.

Xin Liao, Xingfang Yu, Haiping Yu, Jiaqi Huang, Bi Zhang, Jie Xiao

Open access · goldAbstract read
In one paragraph

Article in Journal of nanobiotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Xin Liao *The Second Affiliated Hospital (Jiande Branch), Zhejiang University School of Medicine, Jiande, Hangzhou, Zhejiang, China.
Xingfang Yu *Department of Orthopedics, The Affiliated Yiwu Hospital of Wenzhou Medical University, 699 Jiangdong Road, Yiwu, 322000, Zhejiang, China.
Haiping YuThe Second Affiliated Hospital (Jiande Branch), Zhejiang University School of Medicine, Jiande, Hangzhou, Zhejiang, China.
Jiaqi HuangThe Second Affiliated Hospital (Jiande Branch), Zhejiang University School of Medicine, Jiande, Hangzhou, Zhejiang, China.
Bi ZhangThe Second Affiliated Hospital (Jiande Branch), Zhejiang University School of Medicine, Jiande, Hangzhou, Zhejiang, China.
Jie XiaoThe Second Affiliated Hospital (Jiande Branch), Zhejiang University School of Medicine, Jiande, Hangzhou, Zhejiang, China. jdyyywb2021@163.com.
Second Affiliated Hospital of Zhejiang University · CNWenzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBacterial proliferation on the endosseous implants surface presents a new threat to the using of the bone implants. Unfortunately, there is no effective constructed antibacterial coating which is bacterial anti-adhesion substrate-independent or have long-term biofilm inhibition functions.

methodsDrug release effect was tested in Chymotrypsin (CMS) solution and S. aureus. We used bacterial inhibition rate assays and protein leakage experiment to analyze the in vitro antibacterial effect of (Montmorillonite/Poly-L-lysine-Chlorhexidine)

resultsIn this study, the (MMT/PLL-CHX)

conclusion(MMT/PLL-CHX)

Indexed as

AnimalsAnti-Bacterial AgentsAnti-Infective AgentsBacteriaBacterial AdhesionBentoniteBiofilmsChlorhexidineDisease Models, AnimalDrug ImplantsDrug LiberationMaleRatsRats, Sprague-DawleyStaphylococcal InfectionsStaphylococcus aureusAnti-Bacterial AgentsAnti-Infective AgentsBentoniteChlorhexidineDrug ImplantsAntibacterial effectInfectionsIntraosseous implantsMicroenvironmentMultilayer films

Identifiers

PMID34384446
PMCPMC8359346
OpenAlexW3176795676

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.