Evidence map›Paper›PMID 34384389›Full record

ArticleBMC pregnancy and childbirth2021

Awareness of euglycaemic diabetic ketoacidosis during pregnancy prevents recurrence of devastating outcomes: a case report of two pregnancies in one patient.

Susanne Dargel, Ekkehard Schleußner, Christof Kloos, Tanja Groten, Friederike Weschenfelder

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC pregnancy and childbirth, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Diabetic Ketoacidosis in Pregnancy: A Systematic Review of the Reported Cases.Clinical medicine insights. Endocrinology and diabetes · 2025
    Review
  3. Article
  4. Article
  5. Euglycemic diabetic ketoacidosis in a pregnant woman.Journal of the American College of Emergency Physicians open · 2023
    Article
  6. Diabetic ketoacidosis in pregnancy.BMJ case reports · 2023
    Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Susanne DargelDepartment of Obstetrics, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.
Ekkehard SchleußnerDepartment of Obstetrics, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.
Christof KloosDepartment Internal Medicine III, FB Endocrinology and Metabolic Diseases, Hospital Jena, Jena, Germany.
Tanja GrotenDepartment of Obstetrics, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany. tanja.groten@med.uni-jena.de.ORCID http://orcid.org/0000-0003-3553-4056
Friederike WeschenfelderDepartment of Obstetrics, University Hospital Jena, Am Klinikum 1, 07747, Jena, Germany.
Jena University Hospital · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundEuglycaemic diabetic ketoacidosis (DKA) during pregnancy is a life-threatening obstetric emergency. It requires early identification and prompt action. Obstetricians' knowledge about symptoms, diagnostic pitfalls and management during pregnancy and delivery need to be improved. We report a case of a young diabetic woman developing severe euglycaemic DKA in two consecutive pregnancies; the first pregnancy resulted in the most deviating outcome (i.e., intrauterine death), while the second pregnancy resulted in the delivery of a healthy newborn. Thus, the novelty of the case presented here is the possibility to demonstrate how the management of DKA in pregnancy can dramatically change outcomes. CASE PRESENTATION: We report a case of a young diabetic woman in whom DKA was concealed by hyperemesis and oesophageal reflux. This woman presented to our delivery unit with severe euglycaemic DKA during her first pregnancy. While the mother's condition could be successfully stabilized, the foetus died shortly after admission. Two years later, the same woman presented with similar problems. Repeated episodes of mild euglycaemic DKA could be successfully managed with consequent interdisciplinary treatment and close observation, leading to a good pregnancy outcome, i.e., the birth of a healthy child.

conclusionAwareness of euglycaemic DKA needs to be increased to reduce the risk of severe complications during pregnancies in diabetic women. This case report demonstrates that increased awareness of DKA with immediate recognition and a successful multidisciplinary approach are mandatory for an positive pregnancy outcomes.

Indexed as

Pregnancy in DiabeticsPregnancy OutcomeBirth IntervalsDiabetes Mellitus, Type 1Diabetic KetoacidosisFemaleHumansInfant, NewbornLive BirthPatient Care TeamPregnancyStillbirthYoung AdultCase reportEuglycaemic ketoacidosisPreexisting diabetesPregnancyStillbirth

Identifiers

PMID34384389
PMCPMC8359092
OpenAlexW3192082124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.