Evidence map›Paper›PMID 34384356›Full record

ArticleBMC genomics2021

Mapping of quantitative trait loci underlying a magic trait in ongoing ecological speciation.

Tetsumi Takahashi, Atsushi J Nagano, Teiji Sota

Abstract read
In one paragraph

Article in BMC genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Tetsumi TakahashiInstitute of Natural and Environmental Sciences, University of Hyogo, Sanda, Hyogo, 669-1546, Japan. tetsumi@hitohaku.jp.
Atsushi J NaganoFaculty of Agriculture, Ryukoku University, Otsu, Shiga, 520-2194, Japan.
Teiji SotaGraduate School of Science, Kyoto University, Sakyo, Kyoto, 606-8502, Japan.

Funding

Ministry of Education, Culture, Sports, Science and Technology 18H02499
6 · The paper itself

Abstract

backgroundTelmatochromis temporalis is a cichlid fish endemic to Lake Tanganyika. The normal and dwarf morphs of this fish are a clear example of ongoing ecological speciation, and body size plays an important role in this speciation event as a magic trait. However, the genetic basis underlying this trait has not been studied.

resultsBased on double-digested restriction-site associated DNA (ddRAD) sequencing of a hybrid cross between the morphs that includes F0 male, F0 female, and 206 F2 individuals, we obtained a linkage map consisting of 708 ddRAD markers in 22 linkage groups, which corresponded to the previously reported Oreochromis niloticus chromosomes, and identified one significant and five suggestive quantitative trait loci (QTL) for body size. From the body-size distribution pattern, the significant and three of the five suggestive QTL are possibly associated with genes responsible for the difference in body size between the morphs.

conclusionsThe QTL analysis presented here suggests that multiple genes, rather than a single gene, control morph-specific body size. The present results provide further insights about the genes underlying the morph specific body size and evolution of the magic trait during ecological speciation.

Indexed as

CichlidsQuantitative Trait LociAnimalsChromosome MappingFemaleGenetic LinkageHumansMalePhenotypeBody sizeCichlid fishLake TanganyikaPolygenic inheritanceTelmatochromis temporalis

Identifiers

PMID34384356
PMCPMC8361645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.