Evidence map›Paper›PMID 34384276›Full record

ArticleCartilage2021

Longitudinal Changes in Ultrasound-Assessed Femoral Cartilage Thickness in Individuals from 4 to 6 Months Following Anterior Cruciate Ligament Reconstruction.

Caroline Lisee, Matthew Harkey, Zachary Walker, Karin Pfeiffer, Tracey Covassin, Jeffrey Kovan, Katharine D Currie, Christopher Kuenze

Abstract read
In one paragraph

Article in Cartilage, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Femoral cartilage ultrasound echo-intensity is a valid measure of cartilage composition.Journal of orthopaedic research : official publication of the Orthopaedic Research Society · 2024
    Article
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Caroline LiseeDepartment of Exercise and Sport Science, University of North Carolina at Chapel Hill, NC, USA.ORCID 0000-0003-1771-5734
Matthew HarkeyDepartment of Kinesiology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0002-3480-3173
Zachary WalkerDepartment of Orthopedics, Michigan State University, East Lansing, MI, USA.
Karin PfeifferDepartment of Kinesiology, Michigan State University, East Lansing, MI, USA.
Tracey CovassinDepartment of Kinesiology, Michigan State University, East Lansing, MI, USA.
Jeffrey KovanCollege of Osteopathic Medicine, Michigan State University, East Lansing, MI, USA.
Katharine D CurrieDepartment of Kinesiology, Michigan State University, East Lansing, MI, USA.
Christopher KuenzeDepartment of Kinesiology, Michigan State University, East Lansing, MI, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveDiagnostic ultrasound provides a valid assessment of cartilage health that has been used to observe cross-sectional cartilage thickness differences post-ACLR (anterior cruciate ligament reconstruction), but has not been used longitudinally during early recovery post-ACLR.

designThe purpose of this study was to assess longitudinal changes in femoral cartilage thickness via ultrasound in individuals at 4 to 6 months post-ACLR and compared to healthy controls. Twenty participants (50% female, age = 21.1 ± 5.7 years) completed testing sessions 4 and 6 months post-ACLR. Thirty healthy controls (57% female, age = 20.8 ± 3.8 years) without knee injury history completed 2 testing sessions (>72 hours apart). Femoral cartilage ultrasound images were captured bilaterally in ACLR participants and in the dominant limb of healthy controls during all sessions. Average cartilage thicknesses in the medial, intercondylar, and lateral femoral regions were determined using a semi-automated processing technique.

resultsWhen comparing cartilage thickness mean differences or changes over time, individuals post-ACLR did not demonstrate between limb differences (

conclusionsUsing MDC scores may help better identify within-subject femoral cartilage thickness changes longitudinally post-ACLR due to bidirectional cartilage thickness changes.

Indexed as

Anterior Cruciate Ligament InjuriesAnterior Cruciate Ligament ReconstructionCartilage, ArticularAdolescentAdultCross-Sectional StudiesFemaleHumansKnee JointMaleUltrasonographyYoung Adultknee injuryminimal detectable changesegmentationsemi-automated

Identifiers

PMID34384276
PMCPMC8808943

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.