ReviewAsia-Pacific journal of ophthalmology (Philadelphia, Pa.)
Ethics of Artificial Intelligence in Medicine and Ophthalmology.
Review in Asia-Pacific journal of ophthalmology (Philadelphia, Pa.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
59 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Artificial intelligence in ophthalmology: a bibliometric analysis of the 5-year trends in literature.Frontiers in medicine · 2025Pooled it
- Trends and hotspots in the field of diabetic retinopathy imaging research from 2000-2023.Frontiers in medicine · 2024Pooled it
- Young adults' perceptions and experiences in using mobile apps and wearables for health: a qualitative study with public involvement.BMC public health · 2026Article
- Applications of Generative Artificial Intelligence for Strabismus Surgery Video-Based Education.Ophthalmology science · 2026Article
- Are surgical nurses ready for artificial intelligence? Attitudes toward artificial intelligence technologies in surgical units.BMC nursing · 2026Article
- Artificial Intelligence in Ocular Surface Tumors: Current Advances, Challenges, and Future Directions.Diagnostics (Basel, Switzerland) · 2026Review
- Article
- Patient and clinician perspectives in the use of machine learning and artificial intelligence in the context of acute neurology.JAMIA open · 2025Article
- Artificial Intelligence in Ophthalmology: Practical Applications, Subspecialty Evidence and Real-World Deployment.Cureus · 2025Review
- Evaluating trustworthiness in AI-Based diabetic retinopathy screening: addressing transparency, consent, and privacy challenges.BMC medical ethics · 2025Article
- Current status and solutions for AI ethics in ophthalmology: a bibliometric analysis.NPJ digital medicine · 2025Article
- Role of artificial intelligence in screening and medical imaging of precancerous gastric diseases.World journal of clinical oncology · 2025Review
- Governing Artificial Intelligence in Radiology: A Systematic Review of Ethical, Legal, and Regulatory Frameworks.Diagnostics (Basel, Switzerland) · 2025Review
- A Narrative Review of Ethical Issues in the Use of Artificial Intelligence Enabled Diagnostics for Diabetic Retinopathy.Journal of evaluation in clinical practice · 2025Review
- Selecting the Right AI Algorithm for the Job: A Guide for Navigating the AI Jungle in Ophthalmology.Ophthalmology and therapy · 2025Article
- The acceptance of ophthalmic artificial intelligence for eye diseases: a literature review and qualitative analysis.Eye (London, England) · 2025Review
- Decoding Immunodeficiencies with Artificial Intelligence: A New Era of Precision Medicine.Biomedicines · 2025Review
- Evaluation of ChatGPT-4 as an Online Outpatient Assistant in Puerperal Mastitis Management: Content Analysis of an Observational Study.JMIR medical informatics · 2025Observational
- Artificial intelligence in pancreatic cancer histopathology and diagnostics - implications for clinical decisions and biomarker discovery?Cell division · 2025Review
- Application of Artificial Intelligence in Retinopathy of Prematurity From 2010 to 2023: A Bibliometric Analysis.Health science reports · 2025Article
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5 authors.
Funding
Abstract
backgroundThis review explores the bioethical implementation of artificial intelligence (AI) in medicine and in ophthalmology. AI, which was first introduced in the 1950s, is defined as "the machine simulation of human mental reasoning, decision making, and behavior". The increased power of computing, expansion of storage capacity, and compilation of medical big data helped the AI implementation surge in medical practice and research. Ophthalmology is a leading medical specialty in applying AI in screening, diagnosis, and treatment. The first Food and Drug Administration approved autonomous diagnostic system served to diagnose and classify diabetic retinopathy. Other ophthalmic conditions such as age-related macular degeneration, glaucoma, retinopathy of prematurity, and congenital cataract, among others, implemented AI too. PURPOSE: To review the contemporary literature of the bioethical issues of AI in medicine and ophthalmology, classify ethical issues in medical AI, and suggest possible standardizations of ethical frameworks for AI implementation.
methodsKeywords were searched on Google Scholar and PubMed between October 2019 and April 2020. The results were reviewed, cross-referenced, and summarized. A total of 284 references including articles, books, book chapters, and regulatory reports and statements were reviewed, and those that were relevant were cited in the paper.
resultsMost sources that studied the use of AI in medicine explored the ethical aspects. Bioethical challenges of AI implementation in medicine were categorized into 6 main categories. These include machine training ethics, machine accuracy ethics, patient-related ethics, physician-related ethics, shared ethics, and roles of regulators.
conclusionsThere are multiple stakeholders in the ethical issues surrounding AI in medicine and ophthalmology. Attention to the various aspects of ethics related to AI is important especially with the expanding use of AI. Solutions of ethical problems are envisioned to be multifactorial.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.