ArticleJournal of medical Internet research2021
Obesity and BMI Cut Points for Associated Comorbidities: Electronic Health Record Study.
Article in Journal of medical Internet research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- The effect of obesity interventions on male fertility: a systematic review and meta-analysis.Human reproduction update · 2026Pooled it
- Association of venous thromboembolism prophylaxis with postoperative bleeding in bariatric surgery: an observational study.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2026Article
- Post-operative Hemoglobin Trends for Patients Undergoing Bariatric Surgery: A Retrospective Observational Study.Obesity surgery · 2026Observational
- Single-nucleus analysis of human white adipose tissue reveals adipocyte subsets with distinct metabolic profiles.Nature communications · 2026Article
- Efficacy and safety of orforglipron in obesity with type 2 diabetes mellitus: a GRADE-assessed meta-analysis of randomized controlled trials.Diabetology & metabolic syndrome · 2026Review
- Inclusion bias affects common variant discovery and replication in a health-system linked biobank.American journal of human genetics · 2026Article
- Downstream Impact of a Sleep Surgery Program; Optimizing Patient Care and Generating Clinical Volume.The Laryngoscope · 2026Article
- The comparison of cardiac and body morphometry in patients with non-dipper and reverse-dipper hypertension: a retrospective cross-sectional study.BMC cardiovascular disorders · 2026Article
- Evaluating the economic impact of bariatric surgery: A multi-year comparative analysis.American journal of surgery · 2026Article
- Article
- [Metabolic/bariatric surgery is effective : What is the evidence regarding hard endpoints and long-term outcomes?]Chirurgie (Heidelberg, Germany) · 2026Review
- The overweight and obesity landscape in italy: data from the Italy cohort of the multi-country IMPACT-O study.Journal of endocrinological investigation · 2025Article
- Does a high body mass index remain a protective factor in hip fracture patients with hypertension and diabetes?Aging clinical and experimental research · 2025Article
- Update on esophageal function, acid and non-acid reflux after one-anastomosis gastric bypass (OAGB): high-resolution manometry, impedance-24-h pH-metry, and gastroscopy in a prospective mid-term study.Surgical endoscopy · 2025Article
- Blood lead levels and bladder cancer among US participants: NHANES 1999-2018.BMC public health · 2025Article
- Using Machine Learning to Predict Weight Gain in Adults: an Observational Analysis From the All of Us Research Program.The Journal of surgical research · 2025Observational
- U.S. weight trends: a longitudinal analysis of an NIH-partnered dataset.International journal of obesity (2005) · 2025Article
- Examining Age-Adjusted Associations between BMI and Comorbidities in Mongolia: Cross-Sectional Prevalence.Healthcare (Basel, Switzerland) · 2024Article
- Attitudes and knowledge about weight management among primary care physicians in Israel: a cross-sectional study.BMC primary care · 2024Article
- Managing Adult Obese Patients at Primary Health Care Centers in Qassim Province, Saudi Arabia.Cureus · 2024Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
Abstract
backgroundStudies have found associations between increasing BMIs and the development of various chronic health conditions. The BMI cut points, or thresholds beyond which comorbidity incidence can be accurately detected, are unknown.
objectiveThe aim of this study is to identify whether BMI cut points exist for 11 obesity-related comorbidities.
methodsUS adults aged 18-75 years who had ≥3 health care visits at an academic medical center from 2008 to 2016 were identified from eHealth records. Pregnant patients, patients with cancer, and patients who had undergone bariatric surgery were excluded. Quantile regression, with BMI as the outcome, was used to evaluate the associations between BMI and disease incidence. A comorbidity was determined to have a cut point if the area under the receiver operating curve was >0.6. The cut point was defined as the BMI value that maximized the Youden index.
resultsWe included 243,332 patients in the study cohort. The mean age and BMI were 46.8 (SD 15.3) years and 29.1 kg/m
conclusionsThe BMI cut points that accurately predicted the risks of developing 6 obesity-related comorbidities occurred when patients were overweight or barely met the criteria for class 1 obesity. Further studies using national, longitudinal data are needed to determine whether screening guidelines for appropriate comorbidities may need to be revised.
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