Evidence map›Paper›PMID 34383484›Full record

ArticleAnalytical chemistry2021

Complementary Square-Wave Voltammetry and LC-MS/MS Analysis to Elucidate Induced Damaged and Mutated Mitochondrial and Nuclear DNA from in Vivo Knockdown of the

Elizabeth R LaFave, Michael D Tarpey, Nicholas P Balestrieri, Espen E Spangenburg, Eli G Hvastkovs

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Elizabeth R LaFaveDepartment of Chemistry, East Carolina University, 300 Science and Technology Bldg., Greenville, North Carolina 27858, United States.
Michael D TarpeyDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834, United States.
Nicholas P BalestrieriDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834, United States.
Espen E SpangenburgDepartment of Physiology, Brody School of Medicine, East Carolina University, Greenville, North Carolina 27834, United States.
Eli G HvastkovsDepartment of Chemistry, East Carolina University, 300 Science and Technology Bldg., Greenville, North Carolina 27858, United States.ORCID 0000-0002-7957-9718
East Carolina University · US

Funding

BRCA1 is necessary for optimal skeletal muscle functionR01AR066660 · NIAMS · EAST CAROLINA UNIVERSITY · PI SPANGENBURG, ESPEN E · 2015 to 2019
$1.6M
NIAMS NIH HHS R01 AR066660
6 · The paper itself

Abstract

Breast cancer 1 gene (BRCA1) DNA mutations impact skeletal muscle functions. Inducible skeletal muscle specific Brca1 homozygote knockout (Brca1KO

Indexed as

Genes, BRCA1Tandem Mass SpectrometryAnimalsChromatography, LiquidDNA, MitochondrialMiceMuscle, SkeletalDNA, Mitochondrial

Identifiers

PMID34383484
PMCPMC8796311
OpenAlexW3191178238

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.