Evidence map›Paper›PMID 34383165›Full record

ArticleArchives of virology2021

Taxonomic update for mammalian anelloviruses (family Anelloviridae).

Arvind Varsani, Tanja Opriessnig, Vladimir Celer, Fabrizio Maggi, Hiroaki Okamoto, Anne-Lie Blomström, Dániel Cadar, Balázs Harrach, Philippe Biagini, Simona Kraberger

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in Archives of virology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 81 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
81citing papers in PubMed, 1 pooled it
15.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

81 citing papers in PubMed, 1 synthesis or guideline pooled it, 102 citations in OpenAlex.

  1. Pooled it
  2. Anellovirus-mediated interferon dysregulation enhances virus-induced lung injury.American journal of respiratory cell and molecular biology · 2026
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  12. Molecular Characterization ofInternational journal of molecular sciences · 2026
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  14. Anellovirus protein encoded byProceedings of the National Academy of Sciences of the United States of America · 2025
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  15. Article
  16. Article
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  20. Article

21 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 10 institutions in 10 countries.

Arvind VarsaniThe Biodesign Center for Fundamental and Applied Microbiomics, Center for Evolution and Medicine, School of Life Sciences, Arizona State University, 1001 S. McAllister Ave, Tempe, AZ, 85287-5001, USA. arvind.varsani@asu.edu.ORCID http://orcid.org/0000-0003-4111-2415
Tanja OpriessnigThe Roslin Institute and R(D)SVS, University of Edinburgh, Easter Bush, Midlothian, Scotland, EH25 9RG, UK.
Vladimir CelerFaculty of Veterinary Medicine, University of Veterinary Sciences Brno, Palackeho 1946, 612 42, Brno, Czech Republic.
Fabrizio MaggiDepartment of Medicine and Surgery, University of Insubria, 21100, Varèse, Italy.
Hiroaki OkamotoDivision of Virology, Department of Infection and Immunity, Jichi Medical University School of Medicine, 3311-1 Yakushiji, Shimotsuke-shi, Tochigi, 329-0498, Japan.
Anne-Lie BlomströmDepartment of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences, Uppsala, Sweden.
Dániel CadarWHO Collaborating Centre for Arbovirus and Haemorrhagic Fever Reference and Research, Bernhard Nocht Institute for Tropical Medicine, 20359, Hamburg, Germany.
Balázs HarrachVeterinary Medical Research Institute, Hungária krt. 21, 1143, Budapest, Hungary.
Philippe BiaginiEquipe Biologie des Groupes Sanguins, UMR 7268, ADES, Aix-Marseille Université, CNRS, EFS, 27 Bd. Jean Moulin, 13005, Marseille, France.
Simona KrabergerThe Biodesign Center for Fundamental and Applied Microbiomics, Center for Evolution and Medicine, School of Life Sciences, Arizona State University, 1001 S. McAllister Ave, Tempe, AZ, 85287-5001, USA.
Arizona State University · USBernhard Nocht Institute for Tropical Medicine · DECentre National de la Recherche Scientifique · FRHUN-REN Veterinary Medical Research Institute · HUJichi Medical University · JPRoslin Institute · GBSwedish University of Agricultural Sciences · SEUniversity of Cape Town · ZAUniversity of Insubria · ITUniversity of Veterinary Sciences Brno · CZ

Funding

National Research, Development and Innovation Office - NKFIH NN128309
6 · The paper itself

Abstract

Anelloviruses are small negative-sense single-stranded DNA viruses with genomes ranging in size from 1.6 to 3.9 kb. The family Anelloviridae comprised 14 genera before the present changes. However, in the last five years, a large number of diverse anelloviruses have been identified in various organisms. Here, we undertake a global analysis of mammalian anelloviruses whose full genome sequences have been determined and have an intact open reading frame 1 (ORF1). We established new criteria for the classification of anelloviruses, and, based on our analyses, we establish new genera and species to accommodate the unclassified anelloviruses. We also note that based on the updated species demarcation criteria, some previously assigned species (n = 10) merge with other species. Given the rate at which virus sequence data are accumulating, and with the identification of diverse anelloviruses, we acknowledge that the taxonomy will have to be dynamic and continuously evolve to accommodate new members.

Indexed as

AnelloviridaeAnimalsBase SequenceDatabases, GeneticDNA, ViralGenome, ViralMammalsOpen Reading FramesPhylogenyTerminology as TopicDNA, Viral

Identifiers

PMID34383165
OpenAlexW3187785654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.