Evidence map›Paper›PMID 34383084›Full record

ArticleSocial psychiatry and psychiatric epidemiology2022

Brain structural correlates of upward social mobility in ethnic minority individuals.

Janina I Schweiger, Necip Capraz, Ceren Akdeniz, Urs Braun, Tracie Ebalu, Carolin Moessnang, Oksana Berhe, Zhenxiang Zang, Emanuel Schwarz, Edda Bilek and 2 more

Open access · hybridAbstract read
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In one paragraph

Article in Social psychiatry and psychiatric epidemiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Janina I Schweiger *Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany. janina.schweiger@zi-mannheim.de.ORCID http://orcid.org/0000-0002-8483-9828
Necip Capraz *Department of Psychology, Istanbul Gelisim University, Istanbul, Turkey.
Ceren AkdenizDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany.
Urs BraunDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany.
Tracie EbaluDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany.
Carolin MoessnangDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany.
Oksana BerheDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany.
Zhenxiang ZangDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany.
Emanuel SchwarzDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany.
Edda BilekDepartment of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany.
Andreas Meyer-Lindenberg *Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany.
Heike Tost *Department of Psychiatry and Psychotherapy, Central Institute of Mental Health, Medical Faculty Mannheim, University of Heidelberg, Square J5, 68159, Mannheim, Germany.
Heidelberg University · DEİstanbul Gelişim Üniversitesi · TR

Funding

Bundesministerium für Bildung und Forschung 01KU1905ABundesministerium für Bildung und Forschung grant 01ZX1904ABundesministerium für Bildung und Forschung (DE) 01GQ1003BBundesministerium für Bildung und Forschung (DE) 01GQ1102Bundesministerium für Bildung und Forschung (DE) 01ZX1314GBundesministerium für Bildung und Forschung (DE) grant 01EF1803ABundesministerium für Bildung und Forschung (DE) grant 42-04HV.MED(16)/16/1Bundesministerium für Bildung und Forschung (DE) grants 01EF1803A project WP3Bundesministerium für Bildung und Forschung (DE) MWKDeutsche Forschungsgemeinschaft Collaborative Research Center SFB 1158 project B04Deutsche Forschungsgemeinschaft Collaborative Research Center SFB 1158 project B09Deutsche Forschungsgemeinschaft Collaborative Research Center TRR 265 project A04Deutsche Forschungsgemeinschaft Collaborative Research Center TRR 265 project S02Deutsche Forschungsgemeinschaft grant ME 1591/4-1Deutsche Forschungsgemeinschaft grant SCHW 1768/1-1Deutsche Forschungsgemeinschaft grant TO 539/3-1Deutsche Forschungsgemeinschaft Research Training Group GRK2350/1 project B02FP7 Ideas: European Research Council 115300FP7 Ideas: European Research Council 602805FP7 Ideas: European Research Council FP7FP7 Ideas: European Research Council grant 602450FP7 Ideas: European Research Council HEALTH-F2-2010-241909Innovative Medicines Initiative Joint Undertaking grant 115008Innovative Medicines Initiative Joint Undertaking IMI
6 · The paper itself

Abstract

purposePerigenual anterior cingulate cortex (pACC) is a neural convergence site for social stress-related risk factors for mental health, including ethnic minority status. Current social status, a strong predictor of mental and somatic health, has been related to gray matter volume in this region, but the effects of social mobility over the lifespan are unknown and may differ in minorities. Recent studies suggest a diminished health return of upward social mobility for ethnic minority individuals, potentially due to sustained stress-associated experiences and subsequent activation of the neural stress response system.

methodsTo address this issue, we studied an ethnic minority sample with strong upward social mobility. In a cross-sectional design, we examined 64 young adult native German and 76 ethnic minority individuals with comparable sociodemographic attributes using whole-brain structural magnetic resonance imaging.

resultsResults showed a significant group-dependent interaction between perceived upward social mobility and pACC gray matter volume, with a significant negative association in the ethnic minority individuals. Post-hoc analysis showed a significant mediation of the relationship between perceived upward social mobility and pACC volume by perceived chronic stress, a variable that was significantly correlated with perceived discrimination in our ethnic minority group.

conclusionOur findings extend prior work by pointing to a biological signature of the "allostatic costs" of socioeconomic attainment in socially disadvantaged upwardly mobile individuals in a key neural node implicated in the regulation of stress and negative affect.

Indexed as

EthnicityMinority GroupsCross-Sectional StudiesEthnic and Racial MinoritiesGyrus CinguliHumansSocial MobilityYoung AdultAnterior cingulate gyrusGray matterMental healthSocioeconomic statusStress

Identifiers

PMID34383084
PMCPMC9477908
OpenAlexW3190030042

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.