Evidence map›Paper›PMID 34382787›Full record

ArticleJournal of the American Chemical Society2021

Synthesis of Multi-Protein Complexes through Charge-Directed Sequential Activation of Tyrosine Residues.

Casey S Mogilevsky, Marco J Lobba, Daniel D Brauer, Alan M Marmelstein, Johnathan C Maza, Jamie M Gleason, Jennifer A Doudna, Matthew B Francis

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. DNA-Regulated Multi-Protein Complement Control.Journal of the American Chemical Society · 2024
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Tyrosinase-Catalyzed Peptide Macrocyclization for mRNA Display.Journal of the American Chemical Society · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Evidence for H-bonding interactions to the μ-ηChemical communications (Cambridge, England) · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Casey S MogilevskyDepartment of Chemistry, University of California, Berkeley, California 94720, United States.ORCID 0000-0002-0887-6862
Marco J LobbaDepartment of Chemistry, University of California, Berkeley, California 94720, United States.ORCID 0000-0001-9473-7692
Daniel D BrauerDepartment of Chemistry, University of California, Berkeley, California 94720, United States.ORCID 0000-0001-6974-3476
Alan M MarmelsteinDepartment of Chemistry, University of California, Berkeley, California 94720, United States.ORCID 0000-0003-2024-0602
Johnathan C MazaDepartment of Chemistry, University of California, Berkeley, California 94720, United States.ORCID 0000-0003-2898-8770
Jamie M GleasonDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Jennifer A DoudnaDepartment of Chemistry, University of California, Berkeley, California 94720, United States.
Matthew B FrancisDepartment of Chemistry, University of California, Berkeley, California 94720, United States.ORCID 0000-0003-2837-2538
University of California, Berkeley · USGladstone Institutes · USLawrence Berkeley National Laboratory · US

Funding

Facile Generation of Protein-Protein Conjugates Using Enzymatic Oxidative Coupling ReactionsR01GM138693 · NIGMS · UNIVERSITY OF CALIFORNIA BERKELEY · PI FRANCIS, MATTHEW B · 2020 to 2025
$1.5M
High Performance Computing Cluster for Public Health Driven Molecular Science - Core FacilityS10OD023532 · OD · UNIVERSITY OF CALIFORNIA BERKELEY · PI DURKIN, KATHLEEN A · 2017 to 2017
$434k
NIGMS NIH HHS R01 GM138693NIH HHS S10 OD023532
6 · The paper itself

Abstract

Site-selective protein-protein coupling has long been a goal of chemical biology research. In recent years, that goal has been realized to varying degrees through a number of techniques, including the use of tyrosinase-based coupling strategies. Early publications utilizing tyrosinase from

Indexed as

Bacillus megateriumBenzoquinonesMonophenol MonooxygenaseMutagenesisMutagenesis, Site-DirectedProtein MultimerizationTyrosineBenzoquinonesMonophenol MonooxygenasequinoneTyrosine

Identifiers

PMID34382787
PMCPMC9274618
OpenAlexW3143934431

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.