Evidence map›Paper›PMID 34382586›Full record

ArticleZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences2021

Risk factors for serious infections in inpatients with systemic lupus erythematosus.

Xiujiao Wang, Xiaoxia Zuo, Xiaoyun Xie, Hui Luo, Weiru Zhang, Liping Duan, Hongjun Zhao, Yisha Li, Ya'ou Zhou, Tong Li and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. An Examination of Infection Incidence and Management in Systemic Lupus Erythematosus Patients: A Five-Year Review from a Saudi Arabian Center.Medical science monitor : international medical journal of experimental and clinical research · 2023
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Xiujiao WangDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Xiaoxia ZuoDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Xiaoyun XieDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Hui LuoDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Weiru ZhangDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Liping DuanDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Hongjun ZhaoDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Yisha LiDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Ya'ou ZhouDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Tong LiDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Yanli XieDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Sijia LiuDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Ying JiangDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Shiyao WuDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Jing HuangDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Honglin ZhuDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Junjiao WuDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.
Wangbin NingDepartment of Rheumatology and Immunology, Xiangya Hospital; Institute of Rheumatology and Immunology, Central South University, Changsha 410008.

Funding

the National Natural Science Foundation 81771765the Natural Science Foundation of Hunan Province 2018JJ2638
6 · The paper itself

Abstract

objectivesTo investigate the risk factors for serious infections among hospitalized systemic lupus erythematosus (SLE) patients, and to provide the advice for preventing serious infections in SLE patients.

methodsInformation of SLE patients hospitalized from March 2017 to February 2019 at the Department of Rheumatology and Immunology, Xiangya Hospital, Central South University was obtained. The patients were assigned into a serious infection group and a non-serious infection group. The risk factors for serious infections among SLE inpatients were identified by comparison between the 2 groups and multivariate logistic regression analysis.

resultsThere were 463 SLE inpatients in total, and 144 were in the serious infection group and 319 in the non-serious infection group. Multivariate logistic regression analysis showed that age ≥54.50 years old (OR=4.958,

conclusionsSLE patients with older age, cardiovascular involvement, hematologic involvement, low serum albumin are prone to suffering serious infections. Increased CRP/ESR ratio indicates serious infections in SLE inpatients. High-dose glucocorticoid and the combined use of immunosuppressive agents can increase the risk of serious infections in SLE inpatients.

Indexed as

InpatientsLupus Erythematosus, SystemicAgedGlucocorticoidsHumansMiddle AgedPrednisoneRisk FactorsGlucocorticoidsPrednisoneimmunosuppressive agentsrisk factorsserious infectionssystemic lupus erythematosus

Identifiers

PMID34382586
PMCPMC10930123

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.