Evidence map›Paper›PMID 34382444›Full record

ArticleAmerican journal of rhinology & allergy2022

Temperature-Controlled Radiofrequency Neurolysis for the Treatment of Rhinitis.

Dale Ehmer, Chad M McDuffie, W Cooper Scurry, J Bradley McIntyre, Neelesh H Mehendale, John H Willis, Ronald B Shealy, Jeremy P Watkins, V Vasu Kakarlapudi

Registry-linked trialOpen access · hybridAbstract readMulticenter Study
In one paragraph

Article in American journal of rhinology & allergy, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07323888 (Comparison of Traditional Radiofrequency Ablation of Inferior Turbinates With or Without Posterior Nasal Radiofrequency Ablation), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07323888 naactive not recruitingnot on this mapstarted 2026, after this paper: background citation

Comparison of Traditional Radiofrequency Ablation of Inferior Turbinates With or Without Posterior Nasal Radiofrequency Ablation: A Randomized Controlled Trial

TypeinterventionalSponsorChien Yu HuangRan2026 to 2027Enrolled60ConditionsNasal Obstruction, Chronic Rhinitis, Nonallergic Rhinitis, RhinorrheaArmsTraditional Radiofrequency Ablation of Inferior Turbinates With Posterior Nasal Radiofrequency Ablation, Traditional Radiofrequency Ablation of Inferior Turbinates
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.

  1. Effectiveness of temperature-controlled radiofrequency neurolysis of the posterior nasal nerve to treat chronic rhinitis: a systematic review and meta-analysis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2024
    Pooled it
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  6. Radiofrequency Ablation Versus Laser Neurolysis of the Posterior Nasal Nerve in Patients With Chronic Rhinitis.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Dale EhmerEar, Nose, and Throat Associates of Texas, McKinney, TX, USA.
Chad M McDuffieEar, Nose, and Throat Associates of Texas, McKinney, TX, USA.
W Cooper Scurry161032Piedmont Ear, Nose, and Throat Associates, Winston-Salem, NC, USA.
J Bradley McIntyreFort Worth ENT Group, Fort Worth, TX, USA.
Neelesh H MehendaleEar, Nose, and Throat Associates of Texas, McKinney, TX, USA.
John H Willis161032Piedmont Ear, Nose, and Throat Associates, Winston-Salem, NC, USA.
Ronald B Shealy161032Piedmont Ear, Nose, and Throat Associates, Winston-Salem, NC, USA.
Jeremy P WatkinsFort Worth ENT Group, Fort Worth, TX, USA.
V Vasu KakarlapudiAdvanced ENT and Allergy, New Albany, IN, USA.ORCID https://orcid.org/0000-0001-6694-4598
Charlotte Eye Ear Nose & Throat Associates · USENT and Allergy Associates of Florida · USAdvanced ENT and Allergy · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundChronic rhinitis is a prevalent condition with a significant impact on quality of life. Posterior nasal nerve and vidian neurectomy are surgical options for treating the symptoms of chronic rhinitis but are invasive procedures.

objectiveTo determine the outcomes of patients diagnosed with refractory chronic rhinitis and treated with temperature-controlled radiofrequency neurolysis of the posterior nasal nerve area in a minimally invasive procedure.

methodsA prospective, single-arm multicenter study with follow-up through 52 weeks. Eligible adult patients had chronic rhinitis symptoms of at least 6 months duration with inadequate response to at least 4 weeks usage of intranasal steroids and an overall 12-h reflective total nasal symptom score (rTNSS) ≥ 6 with subscores 2 to 3 for rhinorrhea, 1 to 3 for nasal congestion, and 0 to 3 for each of nasal itching and sneezing. Temperature-controlled radiofrequency energy was delivered to the nasal cavity mucosa overlying the posterior nasal nerve region with a novel single-use, disposable, handheld device.

resultsA total of 50 patients were treated (42.0% male; mean age 57.9 ± 11.9 years), and 47 completed the study through 52 weeks. Mean rTNSS significantly improved from 8.5 (95% CI 8.0, 9.0) at baseline to 3.6 (95% CI 3.0, 4.3) at 52 weeks (

conclusionsTemperature-controlled radiofrequency neurolysis of the posterior nasal nerve area for the treatment of chronic rhinitis is safe and resulted in a durable improvement in the symptoms of chronic rhinitis through a 52-week follow-up. Data suggest that this novel device could be considered a minimally invasive option in the otolaryngologist's armamentarium for the treatment of chronic rhinitis.

Indexed as

RhinitisAdministration, IntranasalAdultAgedFemaleHumansMaleMiddle AgedProspective StudiesQuality of LifeTemperatureTreatment Outcomeallergiccongestionneurectomyneurolysisposterior nasal nerveradiofrequency ablationrhinitisrhinorrhearTNSStemperature-controlled

Identifiers

PMID34382444
PMCPMC8652359
OpenAlexW3187636949

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.