ReviewBiological reviews of the Cambridge Philosophical Society2021
The integrative biology of genetic dominance.
Review in Biological reviews of the Cambridge Philosophical Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Phenotypic dominance emerges from activity fitness functions and molecular interactions.Genetics · 2026Article
- Evolution of dominance in a Mendelian trait is linked to the evolution of environmental plasticity.Evolution; international journal of organic evolution · 2026Article
- Article
- Tuning evolvability via plasmid copy number and regulatory architecture.Nature communications · 2025Article
- Predicted deleterious mutations reveal the genetic architecture of male reproductive success in a lekking bird.Nature ecology & evolution · 2025Article
- Long-term evolutionary persistence of a cryptic color polymorphism in frogs.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Quantifying genetic and genotypic gain gaps in Eucalyptus: the hidden cost of ignoring inbreeding and dominance.Heredity · 2025Article
- A Balanced Inversion Polymorphism Exhibits a Dominance Reversal at the Gene Expression Level that Depends on Developmental Context.Molecular biology and evolution · 2025Article
- Improvement in genetic evaluation of quantitative traits in sheep by enriching genetic model with dominance effects.Scientific reports · 2025Article
- Evolution of GC-biased gene conversion by natural selection.Genetics · 2025Article
- Evolution of dominance in a Mendelian trait is linked to the evolution of environmental plasticity.bioRxiv : the preprint server for biology · 2025Article
- A high-quality assembly revealing the PMEL gene for the unique plumage phenotype in Liancheng ducks.GigaScience · 2025Article
- Dual genetic mechanisms of heterosis: population structure and gene action.Frontiers in plant science · 2025Article
- Article
- Reconciling theories of dominance with the relative rates of adaptive substitution on sex chromosomes and autosomes.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- An explanation for the prevalence of XY over ZW sex determination in species derived from hermaphroditism.Proceedings of the National Academy of Sciences of the United States of America · 2024Article
- Dominance between self-incompatibility alleles determines the mating system ofEvolution letters · 2024Article
- Consequences of partially recessive deleterious genetic variation for the evolution of inversions suppressing recombination between sex chromosomes1.Evolution; international journal of organic evolution · 2024Article
- Fine mapping and identification of the bright green leaf geneFrontiers in plant science · 2024Article
- Analysis of genetic dominance in the UK Biobank.Science (New York, N.Y.) · 2023Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dominance is a basic property of inheritance systems describing the link between a diploid genotype at a single locus and the resulting phenotype. Models for the evolution of dominance have long been framed as an opposition between the irreconcilable views of Fisher in 1928 supporting the role of largely elusive dominance modifiers and Wright in 1929, who viewed dominance as an emerging property of the structure of enzymatic pathways. Recent theoretical and empirical advances however suggest that these opposing views can be reconciled, notably using models investigating the regulation of gene expression and developmental processes. In this more comprehensive framework, phenotypic dominance emerges from departures from linearity between any levels of integration in the genotype-to-phenotype map. Here, we review how these different models illuminate the emergence and evolution of dominance. We then detail recent empirical studies shedding new light on the diversity of molecular and physiological mechanisms underlying dominance and its evolution. By reconciling population genetics and functional biology, we hope our review will facilitate cross-talk among research fields in the integrative study of dominance evolution.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.