ArticleJournal of labelled compounds & radiopharmaceuticals2021
Evaluating N-difluoromethyltriazolium triflate as a precursor for the synthesis of high molar activity [
Article in Journal of labelled compounds & radiopharmaceuticals, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Trifluoromethylation of alkyl electrophiles withScience (New York, N.Y.) · 2025Article
- Broad-scope Syntheses of [Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Article
- Highlight selection of radiochemistry and radiopharmacy developments by editorial board.EJNMMI radiopharmacy and chemistry · 2022Review
- Evaluating N-difluoromethyltriazolium triflate as a precursor for the synthesis of high molar activity [Journal of labelled compounds & radiopharmaceuticals · 2021Article
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Authors and funding
7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
The trifluoromethyl group is a prominent motif in biologically active compounds and therefore of great interest for the labeling with the positron emitter fluorine-18 for positron emission tomography (PET) imaging. Multiple labeling strategies have been explored in the past; however, most of them suffer from low molar activity due to precursor degradation. In this study, the potential of 1-(difluoromethyl)-3-methyl-4-phenyl-1H-1,2,3-triazol-3-ium triflate as precursor for the synthesis of the [
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