ArticleEpilepsy & behavior reports2021
Network radiofrequency ablation for drug resistant epilepsy.
Article in Epilepsy & behavior reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 13 citations in OpenAlex.
- Surgical treatment of epilepsy in polymicrogyria: A subject-level meta-analysis and decision-making framework.Epilepsia · 2026Pooled it
- Efficacy of neurosurgical interventions for epilepsy in polymicrogyria: A systematic review.Epilepsia open · 2026Pooled it
- Stereo-electroencephalography-guided radiofrequency thermocoagulation in patients with implanted neuromodulation devices: patient series.Journal of neurosurgery. Case lessons · 2026Article
- Initial Clinical Experience with the First FDA-Approved sEEG-Guided Radiofrequency Ablation System Featuring Real-Time Temperature Monitoring: A Case Series.Stereotactic and functional neurosurgery · 2026Article
- Direct MRI-guided stereotactic radiofrequency thermal ablation for mesial temporal lobe epilepsy: illustrative cases.Journal of neurosurgery. Case lessons · 2025Article
- Advancing Neuroscience and Therapy: Insights into Genetic and Non-Genetic Neuromodulation Approaches.Cells · 2025Review
- Stereoelectroencephalography-Guided Radiofrequency Thermocoagulation: Diagnostic and Therapeutic Implications.Brain sciences · 2024Review
- An exploratory computational analysis in mice brain networks of widespread epileptic seizure onset locations along with potential strategies for effective intervention and propagation control.Frontiers in computational neuroscience · 2024Article
- Epilepsy Networks and Their Surgical Relevance.Brain sciences · 2023Review
- Radiofrequency ablation during stereoelectroencephalography: from diagnostic tool to therapeutic intervention. Illustrative case.Journal of neurosurgery. Case lessons · 2023Article
- Beyond Resection: Neuromodulation and Minimally Invasive Epilepsy Surgery.Noro psikiyatri arsivi · 2022Review
- Advanced Technology Clinic Provides Personalized Approach to Pediatric Epilepsy Surgery: Early Data and Future Directions.Missouri medicineArticle
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Radiofrequency ablation (RFA) is a minimally invasive procedure for drug-resistant focal epilepsy. Although well tolerated, seizure outcomes are less favorable than standard resection. RFA is commonly performed following stereoencephalography (sEEG) identification of the seizure onset zone (SOZ). We hypothesized RFA outcomes can improve by adding RFA of seizure spread regions to the SOZ as identified by sEEG, an approach we term network RFA. Four patients underwent network RFA at our institution from 8/2017 to 9/2019. There were two Engel IB outcomes and two Engel III outcomes. The median follow-up length was 25.5 months (range 17-35). No permanent neurological deficits occurred. Etiologies consisted of polymicrogyria (1), mixed malformation of cortical development (MCD) (2), and cryptogenic (1). This study provides descriptive results regarding the efficacy and safety of network RFA. Network RFA can be considered in patients with focal epilepsies with large MCDs that may not be amenable to standard resection.
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Registered trials
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