Evidence map›Paper›PMID 34381915›Full record

ArticleArchives of medical sciences. Atherosclerotic diseases2021

Implications of advanced oxidation protein products and vitamin E in atherosclerosis progression.

Leila Azouaou Toualbi, Adnane Mounir, Ballouti Wafa, Arab Medina, Khelfi Abderrezak, Toualbi Chahine, Chader Henni, Bennoui Abdelghani, Seba Atmane

Open access · diamondAbstract read
In one paragraph

Article in Archives of medical sciences. Atherosclerotic diseases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Leila Azouaou ToualbiHospital CHU Parnet Universite Algiers, Algeria.
Adnane MounirDepartment of Biomedicine, Institute of Veterinary Sciences, University of Tiaret, Tiaret, Algeria.
Ballouti WafaDepartment of Biochemistry, Hospital of Parnet, Faculty of Medicine Algiers, Algeria.
Arab MedinaDepartment of Biochemistry, Hospital of CPMC, Faculty of Pharmacy, Algiers, Algeria.
Khelfi AbderrezakDepartment of Toxicology, Hospital of Bab el oued, Faculty of Pharmacy Algiers, Algeria.
Toualbi ChahineDepartment of Orthopedic Surgery, Hospital of Bejaia, Faculty of Medicine, Bejaia, Algeria.
Chader HenniDepartment of Pharmacology, Pastor Institute, Faculty of Pharmacy, Algiers, Algeria.
Bennoui AbdelghaniHospital CHU Parnet Universite Algiers, Algeria.
Seba AtmaneHospital CHU Parnet Universite Algiers, Algeria.
University of Algiers Benyoucef Benkhedda · DZUniversity of Algiers 3 · DZCentre Hospitalo-Universitaire Bab El Oued · DZUniversité IBN Khaldoun Tiaret · DZUniversity of Béjaïa · DZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdvanced oxidation protein products (AOPP) are considered as markers of oxidative stress and inflammation, and highly predictive of atherosclerosis. Vitamin E (Vit-E) is a powerful antioxidant, but no consensus on its effectiveness at the level of AOPP or the process of atherosclerosis has been made. Hence this was the aim of the present study. MATERIAL AND

methodsA longitudinal study was conducted on 205 patients with chronic kidney disease (CKD) and 40 controls. The correlations between AOPP and glomerular filtration rate (GFR) and different biological markers were analyzed. Supra-aortic trunk echo-Doppler was conducted to assess the correlation of AOPP with intima-media thickness. The effects of Vit-E treatment on AOPP levels and atherosclerosis progression were also investigated.

resultsAOPP levels increased in parallel to the alteration of renal functions in CKD patients, compared to the control group (

conclusionsAOPP were proved to be effective markers of oxidative stress and their high levels help to predict the progression of atherosclerosis. As a powerful antioxidant, Vit-E stabilized the AOPP levels.

Indexed as

advanced oxidation protein productsatherosclerosischronic kidney diseaseinflammationvitamin E

Identifiers

PMID34381915
PMCPMC8336440
OpenAlexW3185025963

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.