Evidence map›Paper›PMID 34381811›Full record

ArticleFrontiers in molecular biosciences2021

Chaperonin Abundance Enhances Bacterial Fitness.

C M Santosh Kumar, Kritika Chugh, Anirban Dutta, Vishnuvardhan Mahamkali, Tungadri Bose, Sharmila S Mande, Shekhar C Mande, Peter A Lund

Open access · goldAbstract read
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 3 countries.

C M Santosh KumarSchool of Biosciences and Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom.
Kritika ChughDepartment of Biotechnology and Bioinformatics, University of Rajasthan, Jaipur, India.
Anirban DuttaTCS Research, Tata Consultancy Services Ltd., Pune, India.
Vishnuvardhan MahamkaliAustralian Institute for Bioengineering and Nanotechnology (AIBN), The University of Queensland, Brisbane, QLD, Australia.
Tungadri BoseTCS Research, Tata Consultancy Services Ltd., Pune, India.
Sharmila S MandeTCS Research, Tata Consultancy Services Ltd., Pune, India.
Shekhar C MandeLaboratory of Structural Biology, National Centre for Cell Science (NCCS), Pune, India.
Peter A LundSchool of Biosciences and Institute of Microbiology and Infection, University of Birmingham, Birmingham, United Kingdom.
Tata Consultancy Services (India) · INUniversity of Birmingham · GBNational Centre for Cell Science · INUniversity of Queensland · AUUniversity of Rajasthan · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ability of chaperonins to buffer mutations that affect protein folding pathways suggests that their abundance should be evolutionarily advantageous. Here, we investigate the effect of chaperonin overproduction on cellular fitness in

Indexed as

competitive indexevolutionGroELmetabolic fluxmetabolismproteomics

Identifiers

PMID34381811
PMCPMC8350394
OpenAlexW3187074063

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.