Evidence map›Paper›PMID 34381768›Full record

ArticleFrontiers in bioengineering and biotechnology2021

Novel Cost-Efficient Graphene-Based Impedance Biosensor for the Analysis of Viral Cytopathogenicity and the Effect of Antiviral Drugs.

Anke Schultz, Thorsten Knoll, Andreas Urban, Herbert Schuck, Hagen von Briesen, Anja Germann, Thomas Velten

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

  1. Recent Progresses in Electrochemical DNA Biosensors for SARS-CoV-2 Detection.Frontiers in bioengineering and biotechnology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anke SchultzDepartment of Bioprocessing and Bioanalytics, Fraunhofer Institute for Biomedical Engineering IBMT, Sulzbach, Germany.
Thorsten KnollDepartment of Bioprocessing and Bioanalytics, Fraunhofer Institute for Biomedical Engineering IBMT, Sulzbach, Germany.
Andreas UrbanAiCuris Anti-infective Cures AG, Wuppertal, Germany.
Herbert SchuckDepartment of Bioprocessing and Bioanalytics, Fraunhofer Institute for Biomedical Engineering IBMT, Sulzbach, Germany.
Hagen von BriesenDepartment of Bioprocessing and Bioanalytics, Fraunhofer Institute for Biomedical Engineering IBMT, Sulzbach, Germany.
Anja GermannDepartment of Bioprocessing and Bioanalytics, Fraunhofer Institute for Biomedical Engineering IBMT, Sulzbach, Germany.
Thomas VeltenDepartment of Bioprocessing and Bioanalytics, Fraunhofer Institute for Biomedical Engineering IBMT, Sulzbach, Germany.
Fraunhofer Institute for Biomedical Engineering · DEAiCuris (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biosensors become increasingly relevant for medical diagnostics, pharmaceutical industry, and environmental technology, for example, to test new drugs easily and reliably or to detect cell growth in changing environmental conditions. Novel materials like graphene are promising candidates to produce biosensors on an industrial scale by means of printing processes. To reach this aim, methods for the reliable and automated production of electrode structures and their coating are required. We present an impedance biosensor in the format of a microtiter plate, fabricated by highly efficient roll-to-roll printing of graphene-based microstructures on large-area polymer foils. Proof-of-principle experiments show the evidence of the suitability of the printed graphene biosensors for impedance-based monitoring of viral cytopathogenicity and its inhibition in the presence of antiviral drugs. The developed system is a promising approach toward cost-efficient impedimetric biosensors for high-throughput screening in vaccine research and antiviral drug development.

Indexed as

antiviral drugsgraphene inkgravure printingimpedance biosensorviral cytopathogenicity

Identifiers

PMID34381768
PMCPMC8350578
OpenAlexW3186275440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.