Evidence map›Paper›PMID 34381685›Full record

ArticleRespiratory medicine case reports2021

Slowly progressive interstitial lung disease preceding typical dermatomyositis symptoms in anti-melanoma differentiation-associated gene 5 antibody-positive clinically amyopathic dermatomyositis.

Taisuke Isono, Hiromi Nakajima, Kenji Takano, Yoichi Kobayashi, Yoshinori Kawabata, Yoshihiko Shimizu, Noboru Takayanagi

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Respiratory medicine case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Taisuke IsonoDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
Hiromi NakajimaDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
Kenji TakanoDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
Yoichi KobayashiDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
Yoshinori KawabataDepartments of Pathology, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
Yoshihiko ShimizuDepartments of Pathology, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
Noboru TakayanagiDepartment of Respiratory Medicine, Saitama Cardiovascular and Respiratory Center, Saitama, Japan.
Saitama Prefecture · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 73-year-old woman who visited our hospital complaining of dry cough for three months was refractory to antimicrobial therapy. Chest computed tomography revealed subpleural consolidation. Specimens obtained from surgical lung biopsy revealed subpleural perilobular airspace organization and fibrosis. After the biopsy, mechanic's hand and Gottron's papules appeared, and anti-melanoma differentiation-associated gene 5 (MDA5) antibody was found to be positive. Subsequently, anti-MDA5 antibody measured in cryopreserved serum from her first admission proved to be positive. It is difficult to suspect the presence of anti-MDA-5 antibody in patients with interstitial lung disease without typical dermatomyositis symptoms or slow disease progression.

Indexed as

ANCA, cytoplasmic autoantibodyAnti-melanoma differentiation-associated gene 5BAL, bronchoalveolar lavageCADM, clinically amyopathic dermatomyositisClinically amyopathic dermatomyositisCMV, cytomegalovirusCT, computed tomographyDM, dermatomyositisHRCT, high-resolution computed tomographyILD, interstitial lung diseaseInterstitial lung diseaseIVCY, intravenous cyclophosphamideKL-6, Krebs von den Lungen-6MDA5, anti-melanoma differentiation-associated gene 5PaO2, partial pressure of oxygenPSL, prednisoloneRP-ILD, rapidly progressive interstitial lung diseaseSLB, surgical lung biopsySlowly progressiveSurgical lung biopsyTBLB, transbronchial lung biopsy

Identifiers

PMID34381685
PMCPMC8339249
OpenAlexW3183204698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.