Evidence map›Paper›PMID 34381578›Full record

ReviewSleep science (Sao Paulo, Brazil)

A comprehensive review of obstructive sleep apnea.

Anna Abbasi, Sushilkumar Satish Gupta, Nitin Sabharwal, Vineet Meghrajani, Shaurya Sharma, Stephan Kamholz, Yizhak Kupfer

2 registry-linked trialsOpen access · greenAbstract readReview
In one paragraph

Review in Sleep science (Sao Paulo, Brazil). The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 124 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 6 pooled it
12.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06564896 narecruitingnot on this map

Comparative Assessment of Sleep Positive Airway Pressure Modalities (CASPAM) Trial: Conventional CPAP (AirSense 10) Versus Portable CPAP (AirMini) in Patients With Obstructive Sleep Apnea-A Randomized Crossover Study of User Preference

TypeinterventionalSponsorNational University of MalaysiaRan2024 to 2027Enrolled50ConditionsObstructive Sleep ApneaArmsCPAP Airsense 10 vs Air-Mini
NCT07132307 narecruitingnot on this map

Reducing Obstructive Sleep Apnea After Hypoglossal Nerve Stimulation Through

TypeinterventionalSponsorWashington University School of MedicineRan2025 to 2027Enrolled30ConditionsObstructive Sleep ApneaArmsMandibular advancement device (MAD)
3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 6 syntheses or guidelines pooled it, 160 citations in OpenAlex.

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64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Anna AbbasiMaimonides Medical Center, Medicine - Brooklyn - NY - United States.
Sushilkumar Satish GuptaMaimonides Medical Center, Pulmonary and Critical Care Medicine - Brooklyn - NY - United States.
Nitin SabharwalMaimonides Medical Center, Medicine - Brooklyn - NY - United States.
Vineet MeghrajaniMaimonides Medical Center, Medicine - Brooklyn - NY - United States.
Shaurya SharmaMaimonides Medical Center, Medicine - Brooklyn - NY - United States.
Stephan KamholzMaimonides Medical Center, Medicine - Brooklyn - NY - United States.
Yizhak KupferMaimonides Medical Center, Pulmonary and Critical Care Medicine - Brooklyn - NY - United States.
Maimonides Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Obstructive sleep apnea (OSA) is a complex disorder characterized by collapse of the upper airway during sleep. Downstream effects involve the cardiovascular, pulmonary, and neurocognitive systems. OSA is more prevalent in men than women. Clinical symptoms suggest the diagnosis of OSA but none is pathognomonic of the condition. With rising awareness of OSA and the increasing prevalence of obesity, OSA is increasingly recognized as a major contributor to cardiovascular morbidity including systemic and pulmonary arterial hypertension, heart failure, acute coronary syndromes, atrial fibrillation, and other arrhythmias. Pulmonary manifestations include the development of chronic thromboembolic disease, which can then lead to chronic thromboembolic pulmonary hypertension (CTEPH). Neurocognitive morbidities include stroke and neurobehavioral disorders. Screening for OSA includes the use of symptom questionnaires and the diagnosis is confirmed by polysomnography. Management primarily includes the use of continuous positive airway pressure (CPAP) or bi-level positive airway pressure (BiPAP) devices during sleep. Alternate options such as mandibular devices and surgical procedures are considered for certain patient populations.

Indexed as

Airway ObstructionObstructiveSleep ApneaSleep Apnea Syndromes

Identifiers

PMID34381578
PMCPMC8340897
OpenAlexW3170574920

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.